PathBank

Pathway Description

L-Carnitine Degradation I

Bacteroides sp. 1_1_30

Category:

Metabolite Pathway

Sub-Category:

Metabolic

Created: 2025-01-31

Last Updated: 2025-05-21

L-Carnitine can stimulate anaerobic growth of E.coli when exogenous electron acceptors (i.e. nitrate, etc.) are absent. During anaerobic growth, E.coli can reduce L-carnitine to Î³-butyrobetaine by CoA-linked intermediates when carbon and nitrogen are present in the system. Therefore, L-carnitine may act as external electron acceptor for anaerobic growth as well as generation of an osmoprotectant for cell.

References

L-Carnitine Degradation I References

This pathway was propagated using PathWhiz - Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.

Propagated from SMP0002051

Enter relative concentration values (without units). Elements will be highlighted in a color gradient where red = lowest concentration and green = highest concentration. For the best results, view the pathway in Black and White.

Visualize Compound Data

		3-Dehydroxycarnitine
		Adenosine monophosphate
		Adenosine triphosphate
		Coenzyme A
		Crotonoβinyl-CoA
		diphosphate
		L-Carnitine
		L-Carnitinyl-CoA
		Water
		γ-Butyroβinyl-CoA

Visualize Protein Data

		1,4-dihydroxy-2-naphthoyl-CoA synthase
		Acyl-CoA dehydrogenase
		AMP-binding protein
		Glycoside hydrolase family 5 domain-containing protein
		Major facilitator superfamily (MFS) profile domain-containing protein