PathBank

Pathway Description

L-Carnitine Degradation I

Odoribacter laneus YIT 12061

Category:

Metabolite Pathway

Sub-Category:

Metabolic

Created: 2025-01-31

Last Updated: 2025-06-13

L-Carnitine can stimulate anaerobic growth of E.coli when exogenous electron acceptors (i.e. nitrate, etc.) are absent. During anaerobic growth, E.coli can reduce L-carnitine to Î³-butyrobetaine by CoA-linked intermediates when carbon and nitrogen are present in the system. Therefore, L-carnitine may act as external electron acceptor for anaerobic growth as well as generation of an osmoprotectant for cell.

References

L-Carnitine Degradation I References

This pathway was propagated using PathWhiz - Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.

Propagated from SMP0002051

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Visualize Compound Data

		3-Dehydroxycarnitine
		Adenosine monophosphate
		Adenosine triphosphate
		Coenzyme A
		Crotonoβinyl-CoA
		diphosphate
		L-Carnitine
		L-Carnitinyl-CoA
		Water
		γ-Butyroβinyl-CoA

Visualize Protein Data

		3-hydroxybutyryl-CoA dehydratase
		AMP-dependent synthetase/ligase domain-containing protein
		Butyryl-CoA dehydrogenase
		DUF4136 domain-containing protein
		HTH araC/xylS-type domain-containing protein