PathBank

Pathway Description

L-Carnitine Degradation I

Helicobacter canadensis MIT 98-5491

Category:

Metabolite Pathway

Sub-Category:

Metabolic

Created: 2025-02-01

Last Updated: 2025-08-20

L-Carnitine can stimulate anaerobic growth of E.coli when exogenous electron acceptors (i.e. nitrate, etc.) are absent. During anaerobic growth, E.coli can reduce L-carnitine to Î³-butyrobetaine by CoA-linked intermediates when carbon and nitrogen are present in the system. Therefore, L-carnitine may act as external electron acceptor for anaerobic growth as well as generation of an osmoprotectant for cell.

References

L-Carnitine Degradation I References

This pathway was propagated using PathWhiz - Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.

Propagated from SMP0002051

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Visualize Compound Data

		3-Dehydroxycarnitine
		Adenosine monophosphate
		Adenosine triphosphate
		Coenzyme A
		Crotonoβinyl-CoA
		diphosphate
		L-Carnitine
		L-Carnitinyl-CoA
		Water
		γ-Butyroβinyl-CoA

Visualize Protein Data

		L-aspartate oxidase
		Long-chain fatty acid--CoA ligase
		Probable peptidoglycan glycosyltransferase FtsW
		Putative acyl-CoA dehydrogenase
		Putative filamentous hemagglutinin domain protein