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24892815 PubChem-compound 6022 PubChem-compound 1.0 Phosphocarrier protein HPr 443262 PubChem-compound 3672-15-9 CAS Glycerate kinase 2 937 ChemSpider C00275 KEGG Compound Alpha-mannosidase mngB SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O 1.0 P13669 UniProt 1.0 439278 PubChem-compound Water SMILES O HMDB0000139 HMDB 1.0 C16699 KEGG Compound 473-81-4 CAS HMDB0001341 HMDB Mannose 6-phosphate ReactionCoupledTransportCatalysis226 ACTIVATION Gluconeogenesis from L-Malic Acid SubPathway HMDB0000538 HMDB ATP BioCyc SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1.0 2-O-alpha-Mannosyl-D-glycerate Degradation 2(alpha-D-Mannosyl)-D-glycerate CHEBI:15847 ChEBI ADP BioCyc SMILES [H][C@](CO)(O[C@@]1([H])O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O)[C@]1([H])O)C(O)=O HMDB0001078 HMDB 388334 ChemSpider P0AA04 UniProt 1.0 CHEBI:15422 ChEBI ReactionCatalysis6077 ACTIVATION 388338 ChemSpider 1.0 Escherichia coli 5742 ChemSpider 1038 PubChem-compound 7732-18-5 CAS C3H6O4 Glyceric acid 106.02661 ReactionCatalysis6078 ACTIVATION 1.0 2-O-α-mannosyl-D-glycerate PTS permease C10H16N5O13P3 Adenosine triphosphate 506.99576 HMDB0003391 HMDB CHEBI:32398 ChEBI 1.0 CHEBI:16761 ChEBI 1010 ChemSpider GO:0070258 GENE ONTOLOGY SMP0000839 SMPDB 2-Phospho-D-glyceric acid P23524 UniProt C3H7O7P 2-Phospho-D-glyceric acid 185.99294 Alpha-mannosidase mngB CHEBI:61001 ChEBI C9H16O9 2(alpha-D-Mannosyl)-D-glycerate 268.07944 962 PubChem-compound SMP0002108 SMPDB Hydrogen Ion 5800 ChemSpider CPD0-1063 BioCyc 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate HMDB0012152 HMDB C00631 KEGG Compound Adenosine triphosphate C00080 KEGG Compound PW000819 PathWhiz 439198 PubChem-compound SMILES OC[C@@H](O)C(O)=O HMDB0002111 HMDB Glyceric acid CHEBI:15377 ChEBI ReactionCoupledTransport192 false 2(alpha-D-Mannosyl)-D-glycerate + HPr - phosphorylated → 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate + HPr LEFT_TO_RIGHT C00008 KEGG Compound CHEBI:15378 ChEBI SMILES [H+] CHEBI:17835 ChEBI Glycerate kinase 2 C00001 KEGG Compound 439194 PubChem-compound 58-64-0 CAS P54746 UniProt SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O SubPathwayInteraction3159 SubPathwayReaction SubPathway3159Reaction C9H17O12P 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate 348.04578 Inner Membrane C00002 KEGG Compound Phosphocarrier protein HPr SMILES OC[C@@H](OP(O)(O)=O)C(O)=O 1.0 MANNOSE-6P BioCyc 388411 ChemSpider 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate C00258 KEGG Compound 2-PG BioCyc C6H13O9P Mannose 6-phosphate 260.02972 H2O Water 18.010565 2-O-α-mannosyl-D-glycerate PTS permease 5957 PubChem-compound 1.0 26332075 ChemSpider 562 TAXONOMY H Hydrogen Ion 1.007825 HMDB0059597 HMDB CHEBI:49728 ChEBI PW002096 PathWhiz SMILES OC[C@@H](O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O)C(O)=O 56-65-5 CAS Reaction6117 false Adenosine triphosphate + Glyceric acid → 2-Phospho-D-glyceric acid + Adenosine diphosphate + Hydrogen Ion LEFT_TO_RIGHT Adenosine diphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 3.2.1.170 false 3.2.1.170 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate + Water → Glyceric acid + Mannose 6-phosphate LEFT_TO_RIGHT Alpha- mannosidase mngB Glycerate kinase 2 Phosphocarrier protein HPr Phosphocarrier protein HPr 2-O-α- mannosyl-D- glycerate PTS permease 2-O-(6- Phospho- alpha- mannosyl)-D- glycerate H 2 O Mannose 6-phosphate Glyceric acid ATP 2-Phospho-D- glyceric acid ADP H + 2(alpha-D- Mannosyl)-D- glycerate Gluconeogenesis from L-Malic Acid
24892815 PubChem-compound 6022 PubChem-compound 1.0 Phosphocarrier protein HPr 443262 PubChem-compound 3672-15-9 CAS Glycerate kinase 2 937 ChemSpider C00275 KEGG Compound Alpha-mannosidase mngB SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O 1.0 P13669 UniProt 1.0 439278 PubChem-compound Water SMILES O HMDB0000139 HMDB 1.0 C16699 KEGG Compound 473-81-4 CAS HMDB0001341 HMDB Mannose 6-phosphate ReactionCoupledTransportCatalysis226 ACTIVATION Gluconeogenesis from L-Malic Acid SubPathway HMDB0000538 HMDB ATP BioCyc SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1.0 2-O-alpha-Mannosyl-D-glycerate Degradation 2(alpha-D-Mannosyl)-D-glycerate CHEBI:15847 ChEBI ADP BioCyc SMILES [H][C@](CO)(O[C@@]1([H])O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O)[C@]1([H])O)C(O)=O HMDB0001078 HMDB 388334 ChemSpider P0AA04 UniProt 1.0 CHEBI:15422 ChEBI ReactionCatalysis6077 ACTIVATION 388338 ChemSpider 1.0 Escherichia coli 5742 ChemSpider 1038 PubChem-compound 7732-18-5 CAS C3H6O4 Glyceric acid 106.02661 ReactionCatalysis6078 ACTIVATION 1.0 2-O-α-mannosyl-D-glycerate PTS permease C10H16N5O13P3 Adenosine triphosphate 506.99576 HMDB0003391 HMDB CHEBI:32398 ChEBI 1.0 CHEBI:16761 ChEBI 1010 ChemSpider GO:0070258 GENE ONTOLOGY SMP0000839 SMPDB 2-Phospho-D-glyceric acid P23524 UniProt C3H7O7P 2-Phospho-D-glyceric acid 185.99294 Alpha-mannosidase mngB CHEBI:61001 ChEBI C9H16O9 2(alpha-D-Mannosyl)-D-glycerate 268.07944 962 PubChem-compound SMP0002108 SMPDB Hydrogen Ion 5800 ChemSpider CPD0-1063 BioCyc 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate HMDB0012152 HMDB C00631 KEGG Compound Adenosine triphosphate C00080 KEGG Compound PW000819 PathWhiz 439198 PubChem-compound SMILES OC[C@@H](O)C(O)=O HMDB0002111 HMDB Glyceric acid CHEBI:15377 ChEBI ReactionCoupledTransport192 false 2(alpha-D-Mannosyl)-D-glycerate + HPr - phosphorylated → 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate + HPr LEFT_TO_RIGHT C00008 KEGG Compound CHEBI:15378 ChEBI SMILES [H+] CHEBI:17835 ChEBI Glycerate kinase 2 C00001 KEGG Compound 439194 PubChem-compound 58-64-0 CAS P54746 UniProt SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O SubPathwayInteraction3159 SubPathwayReaction SubPathway3159Reaction C9H17O12P 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate 348.04578 Inner Membrane C00002 KEGG Compound Phosphocarrier protein HPr SMILES OC[C@@H](OP(O)(O)=O)C(O)=O 1.0 MANNOSE-6P BioCyc 388411 ChemSpider 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate C00258 KEGG Compound 2-PG BioCyc C6H13O9P Mannose 6-phosphate 260.02972 H2O Water 18.010565 2-O-α-mannosyl-D-glycerate PTS permease 5957 PubChem-compound 1.0 26332075 ChemSpider 562 TAXONOMY H Hydrogen Ion 1.007825 HMDB0059597 HMDB CHEBI:49728 ChEBI PW002096 PathWhiz SMILES OC[C@@H](O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O)C(O)=O 56-65-5 CAS Reaction6117 false Adenosine triphosphate + Glyceric acid → 2-Phospho-D-glyceric acid + Adenosine diphosphate + Hydrogen Ion LEFT_TO_RIGHT Adenosine diphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 3.2.1.170 false 3.2.1.170 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate + Water → Glyceric acid + Mannose 6-phosphate LEFT_TO_RIGHT mngB garK ptsH ptsH mngR 2-O-(6- Phospho- alpha- mannosyl)-D- glycerate Water Mannose 6-phosphate Glyceric acid Adenosine triphosphate 2-Phospho-D- glyceric acid Adenosine diphosphate Hydrogen Ion 2(alpha-D- Mannosyl)-D- glycerate Gluconeogenesis from L-Malic Acid