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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 200286 results

SMP0119376

Pw120599 View Pathway
Metabolite

Kidney Function

Bos taurus

  • Matched Description: angiotensin II and aldosterone, which increases sodium chloride reabsorption. This results in an … , nutrient reabsorption, and regulating electrolyte concentrations, acid-base balance, extracellular fluid … volume, and blood pressure. The early proximal tubule is where glucose, amino acids, sodium … , chlorine, phosphate, bicarbonate, and water are reabsorbed. Only water is reabsorbed in the thin descending … loop of Henle, while sodium, chlorine and potassium are reabsorbed in the thick ascending loop of
  • Matched Compounds: Aldosterone
  • Matched Proteins: Solute carrier family 3 (Activators of dibasic and neutral amino acid transport), member 2 … Solute carrier family 3 (Cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1
  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

  • Physiological

    SMP0120546

    Pw121802 View Pathway
    Metabolite

    Hartnup Disorder

    Mus musculus

  • Matched Description: -isoleucine, L-leucine, L-phenylalanine, L-serine, L-threonine, L-tryptophan, L-valine, and L-tyrosine in … urine. Symptoms include pellagra, psychosis, ataxia, and mental retardation. Treatment includes nicotinamide.
  • Matched Compounds: Aldosterone
  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3A … Neutral and basic amino acid transport protein rBAT
  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

  • Disease

    SMP0121011

    Pw122278 View Pathway
    Metabolite

    Kidney Function - Collecting Duct

    Homo sapiens

  • Matched Description: release of aldosterone from the adrenal cortex and release of vasopressin from the posterior pituitary … circulation at the collecting duct via potassium and sodium channels. However, aldosterone is a major … The collecting duct of the nephron is the last segment of the functioning nephron and is connected … to minor calyces and the ensuing renal pelvis of the kidney where urine continues before it is … stored in the bladder. The collecting duct is mainly responsible for the excretion and reabsorption of
  • Matched Compounds: Aldosterone
  • Matched Compound Synonyms: [co2(oh)](-) … (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone

  • Physiological

    SMP0120767

    Pw122028 View Pathway
    Metabolite

    Iminoglycinuria

    Rattus norvegicus

  • Matched Description: acid transporter which facilitates the reuptake of glycine, proline, and hydroxyproline. This … disorder is characterized by a large accumulation of glycine, proline, and hydroxyproline in the urine … . Symptoms of the disorder include urolithiasis and mental retardation.
  • Matched Compounds: Aldosterone
  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT
  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

  • Disease

    SMP0120548

    Pw121804 View Pathway
    Metabolite

    Lysinuric Protein Intolerance

    Mus musculus

  • Matched Description: enzyme results in accumulation of ammmonia and reticulocytes in blood; glutamine in plasma, carnitine … and ferritin in serum, and arginine, lysine and ornithine in urine. Symptoms include bone marrow … abnormality, growth retardation, hyperammoniemia, mental retardation, pancreatitis, and seizures.
  • Matched Compounds: Aldosterone
  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3A … Neutral and basic amino acid transport protein rBAT
  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

  • Disease

    SMP0000086

    Pw000131 View Pathway
    Metabolite

    Ibuprofen Action Pathway

    Homo sapiens

  • Matched Description: Ibuprofen is a very common NSAID drug used to treat pain and inflammation. This includes headaches … , muscle pain and fever. It is sold under the brand name Advil or Motrin. Ibuprofen is typically … prostaglandin G/H synthase (COX). These enzymes are available as COX1 and COX2, and are encoded by … PTGS1 (COX1) and PTGS2 (COX2). Ibuprofen may also inhibit fatty acid amide hydrolase (FAAH), which
  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))
  • Matched Protein Synonyms: Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20
  • Matched Compound Synonyms: 20-oh-leukotriene b4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-ltb4 … 20-carboxy-leukotriene b4

  • Drug Action

    SMP0123094

    Pw124439 View Pathway
    Metabolite

    Quinapril ACE Inhibitor Action Pathway

    Homo sapiens

  • Matched Description: production of aldosterone which increases salt and water retention which increases blood volume. Less … vasoconstrictive effects and increases blood pressure. Quinapril is used to treat hypertension, high blood … pressure, congestive heart failure, and chronic renal failure as it decreases blood pressure … angiotensin II type 1 receptor (AT1) in blood vessels, kidneys, hypothalamus, and posterior pituitary … angiotensin II reduces aldosterone production allowing water retention to not increase. AT1 receptors in
  • Matched Compounds: Aldosterone
  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone

  • Drug Action

    SMP0124966

    Pw126473 View Pathway
    Metabolite

    Forasartan Angiotensin Blocker Action Pathway

    Homo sapiens

  • Matched Description: and water retention which increases blood volume. Blocking AT1 receptors reduces aldosterone … that has powerful vasoconstrictive effects and increases blood pressure. Forasartan used to treat … receptors (AT1) in blood vessels, kidneys, hypothalamus, and posterior pituitary. In blood vessels AT1 … . AT1 receptors in the kidney are responsible for the production of aldosterone which increases salt
  • Matched Compounds: Aldosterone
  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone

  • Drug Action

    SMP0126015

    Pw127589 View Pathway
    Metabolite

    Saprisartan Action Pathway

    Homo sapiens

  • Matched Description: II. By inhibiting those actions, saprosartan leads to a decrease in sodium reabsorpion and a decrease
  • Matched Compounds: Aldosterone
  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone

  • Drug Action

    SMP0123095

    Pw124440 View Pathway
    Metabolite

    Ramipril ACE Inhibitor Action Pathway

    Homo sapiens

  • Matched Description: production of aldosterone which increases salt and water retention which increases blood volume. Less … vasoconstrictive effects and increases blood pressure. Ramipril is used to treat hypertension, high blood … pressure, congestive heart failure, and chronic renal failure as it decreases blood pressure … angiotensin II type 1 receptor (AT1) in blood vessels, kidneys, hypothalamus, and posterior pituitary … angiotensin II reduces aldosterone production allowing water retention to not increase. AT1 receptors in
  • Matched Compounds: Aldosterone
  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone

  • Drug Action