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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 508419 results

SMP0120647

Pw121903 View Pathway
Metabolite

Blue Diaper Syndrome

Mus musculus

  • Matched Description: symptoms can include bacterial infections, damage to various parts of the eye, hypercalcemia, and impaired … hypercalcemia, and a tryptophan restricted diet to prevent all systems. If bacterial infections are common, antibiotics may be prescribed.
  • Matched Compounds: Aldosterone
  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3A … Neutral and basic amino acid transport protein rBAT
  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

  • Disease

    SMP0122731

    Pw124055 View Pathway
    Metabolite

    Eplerenone Action Pathway

    Homo sapiens

  • Matched Description: occurs via the aquaporins. Aldosterone is released from the adrenal cortex of the kidney and acts on the … and blocks aldosterone binding. This prevents the aldosterone effects on gene transcription … Eplerenone is an oral drug used to treat conditions such as hypertension and congestive heart … duct, sodium and water reabsorption occur, along with potassium excretion. The sodium channel (ENaC … the lumen where it is excreted in urine. Water reabsorption is linked to Na+ reabsorption and
  • Matched Compounds: Aldosterone
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (+)-aldosterone

  • Drug Action

    SMP0121011

    Pw122278 View Pathway
    Metabolite

    Kidney Function - Collecting Duct

    Homo sapiens

  • Matched Description: release of aldosterone from the adrenal cortex and release of vasopressin from the posterior pituitary … circulation at the collecting duct via potassium and sodium channels. However, aldosterone is a major … The collecting duct of the nephron is the last segment of the functioning nephron and is connected … to minor calyces and the ensuing renal pelvis of the kidney where urine continues before it is … stored in the bladder. The collecting duct is mainly responsible for the excretion and reabsorption of
  • Matched Compounds: Aldosterone
  • Matched Compound Synonyms: [co2(oh)](-) … (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone

  • Physiological

    SMP0123092

    Pw124437 View Pathway
    Metabolite

    Moexipril ACE Inhibitor Action Pathway

    Homo sapiens

  • Matched Description: production of aldosterone which increases salt and water retention which increases blood volume. Less … vasoconstrictive effects and increases blood pressure. Moexipril is used to treat hypertension, high … blood pressure, congestive heart failure, and chronic renal failure as it decreases blood pressure … to angiotensin II type 1 receptor (AT1) in blood vessels, kidneys, hypothalamus, and posterior … angiotensin II reduces aldosterone production allowing water retention to not increase. AT1 receptors
  • Matched Compounds: Aldosterone
  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone

  • Drug Action

    SMP0123104

    Pw124449 View Pathway
    Metabolite

    Trandolapril ACE Inhibitor Action Pathway

    Homo sapiens

  • Matched Description: for the production of aldosterone which increases salt and water retention which increases blood … vasoconstrictive effects and increases blood pressure. Trandolapril is used to treat hypertension … , high blood pressure, congestive heart failure, and chronic renal failure as it decreases blood pressure … by binding to angiotensin II type 1 receptor (AT1) in blood vessels, kidneys, hypothalamus, and … volume. Less angiotensin II reduces aldosterone production allowing water retention to not increase
  • Matched Compounds: Aldosterone
  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone

  • Drug Action

    SMP0124964

    Pw126471 View Pathway
    Metabolite

    Candesartan Action Pathway (New)

    Homo sapiens

  • Matched Description: aldosterone which increases salt and water retention which increases blood volume. Blocking AT1 … that has powerful vasoconstrictive effects and increases blood pressure. Candesartan is used to treat … to angiotensin II type 1 receptors (AT1) in blood vessels, kidneys, hypothalamus, and posterior … receptors reduces aldosterone production allowing water retention to not increase. AT1 receptors in the … effects of taking candesartan are symptomatic hypotension, abnormal renal function, and
  • Matched Compounds: Aldosterone
  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone

  • Drug Action

    SMP0124969

    Pw126476 View Pathway
    Metabolite

    Telmisartan Action Pathway (New)

    Homo sapiens

  • Matched Description: for the production of aldosterone which increases salt and water retention which increases blood … that has powerful vasoconstrictive effects and increases blood pressure. Telmisartan used to treat … hypertension, diabetic nephropathy, and congestive heart failure. Angiotensin has many … , hypothalamus, and posterior pituitary. In blood vessels AT1 receptors cause vasoconstriction in the tunica … volume. Blocking AT1 receptors reduces aldosterone production allowing water retention to not increase
  • Matched Compounds: Aldosterone
  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone

  • Drug Action

    SMP0126013

    Pw127587 View Pathway
    Metabolite

    Tasosartan Action Pathway

    Homo sapiens

  • Matched Description: , reduced secretion of avsopressin (ADH), and reduced production and secretion of aldosterone. … the treatment of hypertension and heart failure. This drug causes the blockade of the renin … -angiotensin-aldosterone system (RAAS) at the level of the AT1 receptor. Tasosartan is an antagonist of the AT1 … receptors localize in the vascular muscles and the adrenal gland. This drug thus causes dilatation
  • Matched Compounds: Aldosterone
  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone

  • Drug Action

    SMP0122986

    Pw124329 View Pathway
    Metabolite

    Cilazapril ACE inhibitor Action Pathway

    Homo sapiens

  • Matched Description: well, reducing aldosterone and vasopressin secretion, inhibiting vasoconstriction, and allowing the … uptake of sodium and insufficient potassium excretion due to reduced aldosterone levels. Cilazapril is eliminated by the kidneys and excreted through urination. … treat hypertension and heart failure as it reduces the effects of angiotensin II which decreases … resistance and blood pressure, as angiotensin II is a potent vasoconstrictor. Angiotensin II is produced … the kidneys, blood vessels, posterior pituitary gland and excitatory amino acid transporter via
  • Matched Compounds: Aldosterone
  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone

  • Drug Action

    SMP0124966

    Pw126473 View Pathway
    Metabolite

    Forasartan Angiotensin Blocker Action Pathway

    Homo sapiens

  • Matched Description: and water retention which increases blood volume. Blocking AT1 receptors reduces aldosterone … that has powerful vasoconstrictive effects and increases blood pressure. Forasartan used to treat … receptors (AT1) in blood vessels, kidneys, hypothalamus, and posterior pituitary. In blood vessels AT1 … . AT1 receptors in the kidney are responsible for the production of aldosterone which increases salt
  • Matched Compounds: Aldosterone
  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone

  • Drug Action