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Matched Description: the effects of aldosterone on electrolyte and water excretion, refer to the description of the … .) to prevent increasing sodium, water reabsorption and peripheral resistance (that will lead to … increasing blood pressure) via aldosterone secretion that is caused by angiotensin II. Therefore … /pathways/SMP00132/pathway pathway, which describes the mechanism of direct aldosterone antagonists … . Candesartan is an effective agent for reducing blood pressure and may be used to treat essential hypertension and heart failure.

Matched Compounds: Aldosterone

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone

Matched Description: blood pressure. For more information on the effects of aldosterone on electrolyte and water … . vascular smooth muscle, the adrenal glands, etc.) to prevent increasing sodium, water reabsorption and … peripheral resistance (that will lead to increasing blood pressure) via aldosterone secretion that … mechanism of direct aldosterone antagonists. Valsartan is an effective agent for reducing blood … pressure and may be used to treat essential hypertension and heart failure.

Matched Compounds: Aldosterone

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone

Matched Description: liver. 4-Hydroxyifosfamide crosses the plasma membrane of the cancer cell and spontaneuosly forms … aldoifosfamide. This is a reversible reaction. Aldoifosfamide can decompose into acrolein and ifosforamide … mustard. Ifosforamide mustard is the active alkylating agent and forms alkyl adducts with DNA … through an ifosforamide aziridinium intermediate. Alkylation of DNA causes DNA damage and ultimately cell death.

Matched Protein Synonyms: Cytochrome P450 MP-20

Matched Compound Synonyms: Magnacide h and b … [oh(oh)]

Matched Description: enzyme (ACE) is a component of the body's renin–angiotensin–aldosterone system (RAAS) and cleaves … angiotensin-converting enzyme (ACE) inhibitors and is used primarily to lower high blood pressure … (hypertension). This drug can also be used in the treatment of congestive heart failure and type II diabetes … concentrations and increase bradykinin concentrations resulting in blood vessel dilation and thereby lowering blood pressure.

Matched Compounds: Aldosterone

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone

Matched Description: component of the body's renin–angiotensin–aldosterone system (RAAS) and cleaves inactive angiotensin I into … (ACE) inhibitors and is used primarily to lower high blood pressure (hypertension). This drug can … also be used in the treatment of congestive heart failure and type II diabetes. Ramipril is a prodrug … vasodilator bradykinin. Consequently, ACE inhibitors decrease angiotensin II concentrations and increase … bradykinin concentrations resulting in blood vessel dilation and thereby lowering blood pressure.

Matched Compounds: Aldosterone

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone

Matched Description: reabsorption and peripheral resistance (that will lead to increasing blood pressure) via aldosterone secretion … decreasing blood pressure. For more information on the effects of aldosterone on electrolyte and water … the mechanism of direct aldosterone antagonists. Losartan is an effective agent for reducing blood … pressure and may be used to treat essential hypertension and heart failure.

Matched Compounds: Aldosterone

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone

Matched Description: are degradation of bradykinin, substance P, and amyloid beta-protein. Angiotensin converting enzyme … (ACE) is well known for its dual actions in converting inactive Ang I to active Ang II and degrade … bottle neck step is the production of pressor Ang II, this was targeted pharmacologically in 1970s and … of an epidemic in 2002–2003. Two isozymes of ACE are present in mammals: somatic ACE and testis ACE … . Somatic ACE possesses two catalytic domains (N- and C-domains) and a C-terminal transmembrane

Matched Compounds: Aldosterone

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone

Matched Description: the release of aldosterone from the adrenal cortex and release of vasopressin from the posterior … The distal convoluted tubule of the nephron is the part of the kidney between the loop of henle and … reabsorption back into the blood circulation. In addition, sodium, chlorine, and calcium are also … reabsorbed back into the systemic circulation via their respective channels and exchangers. However … , aldosterone is a major regulator of the reabsorption of these ions as well, as it changes the

Matched Compounds: Aldosterone

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone

Matched Description: Phenylketonuria, also called Folling disease, is a rare inborn error of metabolism (IEM) and … disorder is characterized by a large accumulation of phenylalanine in the blood and other tissues. It is … , Phenylacetylglutamine, and Glycine in the blood and urine. Symptoms of the disorder include behavioural … problems, psychiatric disorders and seizures. Treatment eating a diet limiting the intake of

Matched Proteins: Sodium- and chloride-dependent creatine transporter 1

Matched Compound Synonyms: 2-oxo-3-phenylpropanoic acid (mixture oxo and keto) … Ammonia (conc 20% or greater) … [oh(oh)] … Ammonia (conc 20% or greater) … [oh(oh)]

Matched Description: isozymes in the liver. 4-Hydroxyphosphamide is more soluble than cyclophosphamide and is the primary form … cancer cell and spontaneuosly forms aldophosphamide. This is a reversible reaction. Aldophosphamide can … decompose into acrolein and phosphoramide mustard. Phosphoramide mustard is the active alkylating … agent and forms alkyl adducts with DNA through a phosphoramide aziridinium intermediate. Alkylation … of DNA causes DNA damage and eventually cell death.

Matched Protein Synonyms: Cytochrome P450 MP-20

Matched Compound Synonyms: Magnacide h and b … [oh(oh)]