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Matched Description: component of the body's renin–angiotensin–aldosterone system (RAAS) and cleaves inactive angiotensin … enzyme (ACE) inhibitors and is used primarily to lower high blood pressure (hypertension). This drug can … also be used in the treatment of congestive heart failure and type II diabetes. Temocapril is a … vasodilator bradykinin. Consequently, ACE inhibitors decrease angiotensin II concentrations and increase … bradykinin concentrations resulting in blood vessel dilation and thereby lowering blood pressure.

Matched Compounds: Aldosterone

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone

Matched Description: reabsorption and peripheral resistance (that will lead to increasing blood pressure) via aldosterone secretion … decreasing blood pressure. For more information on the effects of aldosterone on electrolyte and water … describes the mechanism of direct aldosterone antagonists. Telmisartan is an effective agent for reducing … blood pressure and may be used to treat essential hypertension and heart failure.

Matched Compounds: Aldosterone

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone

Matched Description: cholesterol. Aldosterone then goes to act on the distal convoluted tubule and the collecting duct to make … regulating fluid homeostasis and blood pressure. It is involved in various means to increase the body's … blood pressure, hence why it is a target for many pharmceutical drugs that treat hypertension and … vasoconstriction and a subsequent increase in blood pressure. However, it can also influence the blood pressure … in the supraoptic nuclei and they travel down the neurosecretory neuron axon to be stored in the

Matched Compounds: Aldosterone

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone

Matched Description: and IUDs have a low dose, while emergency contraceptives (Plan B) are administered at high doses … . This drug's contraceptive function delays or inhibits ovulation and thickens cervical mucus to prevent … pregnancy before fertilization and implantation. This drug can also be used for hormone therapy in … it binds to the progesterone and the androgen receptors. This binding inhibits the release of … migration into the uterus for fertilization. An overdose of levonorgestrel may cause nausea and withdrawal bleeding.

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one

Matched Description: endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. It is used as an … oral drug as a contraceptive to prevent ovulation and fertilization in certain formulations, as well … from a plant source as a starting material and is chemically identical to progesterone of human ovarian … origin. Progesterone binds its receptor (located both on the membrane and in the cytosol) which … concentration of GnRH results in the transcription of less LH and FSH hormones by the pituitary gland

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one

Matched Description: Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) in the pituitary gland. This prevents

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one

Matched Description: , Angeliq, and Loryna. This drug is also indicated to control acne, menopause-associated symptoms, and … inhibiting the release of the Luteinizing Hormone (LH) and the Follicle-Stimulating Hormone (FSH) in the … dihydrotestosterone (DHT) to its receptor, and preventing androgen synthesis in the ovaries, helping to treat … acne and hirsutism. An overdose of this drug will lead to nausea or withdrawal bleeding, like other oral contraceptives.

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one

Matched Description: levonorgestrel and the other one is dextronorgestrel. This drug is used in combination with ethinyl estradiol … for oral contraception and prevention of pregnancy in women. Levonorgestrel (the active stereoisomer … of norgestrel) binds the progesterone and estrogen receptors. Those receptors are found in the … mammary glands, the hypothalamus, and in the pituitary gland. With this binding, levonorgestrel inhibits … and downgrades the level of secretion of gonadotropin-releasing hormone (GnRH) from the hypothalamus

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one

Matched Description: receptors, nicotinic acetylcholine receptors, and sigma-1 receptors. Dextromethorphan is an agonist … of NMDA and sigma-1 receptors. It is an antagonist of neuronal acetylcholine receptors, especially … subunit 3A and prevents glutamate from binding to the NDMA receptor on the epsilon-2 subunit. This … prevents the calcium channel from opening and allowing calcium into to the post-synaptic neuron. With … reticulum of central nervous system neurons, where they regulate calcium and potassium, but the reason

Matched Compound Synonyms: Ammonia (conc 20% or greater) … Tylenol cold and flu multi-symptom … Tylenol cold and flu no drowsiness … Tylenol cold and flu multi-symptom … Tylenol cold and flu no drowsiness

Matched Description: . Nowadays, it is used as a drug to treat anorexia and cachexia (or unexplained weight loss) and as an … antineoplastic agent to treat inoperable breast cancer, endometrial cancer, and prostate cancer … secretory changes in the endometrium, increase in basal body temperature, and pituitary inhibition … . By inhibiting the release of GnRH in the hypothalamus, there is a decrease in LH and FSH synthesis in … antianorexic and anticachetic is undetermined. It is thought to act by stimulating the appetite or by

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one