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Matched Description: cholesterol. Aldosterone then goes to act on the distal convoluted tubule and the collecting duct to make … regulating fluid homeostasis and blood pressure. It is involved in various means to increase the body's … blood pressure, hence why it is a target for many pharmceutical drugs that treat hypertension and … vasoconstriction and a subsequent increase in blood pressure. However, it can also influence the blood pressure … in the supraoptic nuclei and they travel down the neurosecretory neuron axon to be stored in the

Matched Compounds: Aldosterone

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone

Matched Description: hypothalamus, and the pituitary. By those binding, this drug reduces the secretion of GnRH from the … increases the viscosity of the cervical mucus. This blocks the passage of spermatozoa and alters the

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one

Matched Description: contraception, prevention of endometrial hyperplasia (hormone replacement therapy), and in the treatment of … greater potency. This drug acts by altering the cervical and endometrial function, as well as it … inhibits the pituitary hormones, like the Follicle-stimulating hormone (FSH) and the Luteinizing … hormone (GnRH) production in the hypothalamus. The low levels of LH and FSH result in the inhibition of … the production of estrogen in the ovaries, thus inhibiting follicular maturation, ovulation, and

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one

Matched Description: and IUDs have a low dose, while emergency contraceptives (Plan B) are administered at high doses … . This drug's contraceptive function delays or inhibits ovulation and thickens cervical mucus to prevent … pregnancy before fertilization and implantation. This drug can also be used for hormone therapy in … it binds to the progesterone and the androgen receptors. This binding inhibits the release of … migration into the uterus for fertilization. An overdose of levonorgestrel may cause nausea and withdrawal bleeding.

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one

Matched Description: endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. It is used as an … oral drug as a contraceptive to prevent ovulation and fertilization in certain formulations, as well … from a plant source as a starting material and is chemically identical to progesterone of human ovarian … origin. Progesterone binds its receptor (located both on the membrane and in the cytosol) which … concentration of GnRH results in the transcription of less LH and FSH hormones by the pituitary gland

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one

Matched Description: Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) in the pituitary gland. This prevents

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one

Matched Description: . Nowadays, it is used as a drug to treat anorexia and cachexia (or unexplained weight loss) and as an … antineoplastic agent to treat inoperable breast cancer, endometrial cancer, and prostate cancer … secretory changes in the endometrium, increase in basal body temperature, and pituitary inhibition … . By inhibiting the release of GnRH in the hypothalamus, there is a decrease in LH and FSH synthesis in … antianorexic and anticachetic is undetermined. It is thought to act by stimulating the appetite or by

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one

Matched Description: Dienogest is a semisynthetic progestogen derived from 19-nortestosterone and has antiandrogenic … , which suppresses the effects of oestradiol on both the eutopic and ectopic endometrium (anovulation … like acne and hirsutism. This drug is administered as an oral tablet.

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one

Matched Description: levonorgestrel and the other one is dextronorgestrel. This drug is used in combination with ethinyl estradiol … for oral contraception and prevention of pregnancy in women. Levonorgestrel (the active stereoisomer … of norgestrel) binds the progesterone and estrogen receptors. Those receptors are found in the … mammary glands, the hypothalamus, and in the pituitary gland. With this binding, levonorgestrel inhibits … and downgrades the level of secretion of gonadotropin-releasing hormone (GnRH) from the hypothalamus

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one

Matched Description: , Angeliq, and Loryna. This drug is also indicated to control acne, menopause-associated symptoms, and … inhibiting the release of the Luteinizing Hormone (LH) and the Follicle-Stimulating Hormone (FSH) in the … dihydrotestosterone (DHT) to its receptor, and preventing androgen synthesis in the ovaries, helping to treat … acne and hirsutism. An overdose of this drug will lead to nausea or withdrawal bleeding, like other oral contraceptives.

Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD

Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one