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Matched Description: enhance the image in cranial and spinal MRIs. It is used with magnetic resonance imaging (MRI) in adults … , and pediatric patients (2 years of age and older) to visualize lesions with abnormal vascularity in … the brain (intracranial lesions), spine and associated tissues as well as lesions with abnormal … vascularity in the head and neck. Also used to facilitate the visualization of lesions with abnormal

Matched Description: system within the immune system. This pathway begins with the activation of antibodies IgM and IgG … . Protein C3 is created, and after a series of reactions, cleaves the C5 protein. This brings phagocytes … to the infected area and sets the stage for the coming together of the membrane attack complex (MAC … ). This complex targets the cell and creates an opening in the membrane, which leads to cell lysis and death.

Matched Description: system within the immune system. This pathway begins with the activation of antibodies IgM and IgG … . Protein C3 is created, and after a series of reactions, cleaves the C5 protein. This brings phagocytes … to the infected area and sets the stage for the coming together of the membrane attack complex (MAC … ). This complex targets the cell and creates an opening in the membrane, which leads to cell lysis and death.

Matched Description: not been fully elucidated; however, it is understood that venlafaxine and its active metabolite O … -desmethylvenlafaxine (ODV) commonly called desvenlafaxine potently and selectively inhibits the … reuptake of both serotonin and norepinephrine at the presynaptic terminal. This results in increased … : venlafaxine initially inhibits serotonin reuptake at low doses, and with higher doses, it inhibits … norepinephrine reuptake in addition to serotonin. Venlafaxine and desvenlafaxine are also weak inhibitors of dopamine reuptake.

Matched Description: Salmeterol is a long acting beta-2 adrenergic receptor agonists used to treat asthma and COPD. Beta … , Airduo, Serevent, and Wixela. This drug is to be inhaled alongside corticosteroids to be most … effective. It is useful for the prevention of exercise induced bronchospasm and airflow obstruction … . Salmeterol can bind to both active and exo sites on the beta-2 adrenergic receptor; the saligenin moiety … binds to the active site and the hydrophilic tail binds to leucine residues in the exo site almost

Matched Description: hypotensive states and as an adjunct treatment during cardiac arrest. It can be found under the brand name … Levophed. Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central … and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic … sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus … . It is also found in plants and is used pharmacologically as a sympathomimetic. Noradrenaline acts

Matched Description: Protein C is also known under brand names such as Balfaxar, Beriplex, Ceprotin, Kcentra and … Octaplex used to treat purpura fulminans and or coumarin-induced skin necrosis. Protein C is an endogenous … and VIII, decreasing clot formation. Due to its anticoagulant nature herbs and supplements with … similar activity should be avoided such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba.

Matched Description: Apixaban is an oral anticoagulant drug that competitively inhibits free and bound coagulation … strokes or systemic embolism. Used in the treatment and prevention of recurrent thromboembolic diseases … , such as deep vein thrombosis and pulmonary embolisms. Apixaban is metabolized by both CYP3A4 and P … -glycoprotein (P-gp) and is known to increase in the blood when these are inhibited. Apixaban enters

Matched Description: , P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis … accumulate toxic heme, killing the parasite. Chloroquine passively diffuses through cell membranes and into … endosomes, lysosomes, and Golgi vesicles; where it becomes protonated, trapping the chloroquine in … the organelle and raising the surrounding pH. The raised pH in endosomes, prevent virus particles … from utilizing their activity for fusion and entry into the cell.

Matched Description: , including VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). Lenvatinib also inhibits other RTKs, such … as fibroblast growth factor receptors (FGFR1, 2, 3, and 4), the platelet-derived growth factor … receptor alpha (PDGFRα), KIT, and RET, all of which play crucial roles in processes like angiogenesis … , tumor growth, and cancer progression. Its approved indications include metastatic thyroid cancer … , advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma