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Matched Description: Folate biosynthesis is a pathway by which pterin and pABA precursors form tetrahydrofolate, an … . Although tetrahydrofolate is synthesized in the mitochondrial matrix, the pterin and pABA branches … occur in the cytosol and the chloroplast, respectively. The first reaction in the pABA branch is … catalyzed by aminodeoxychorismate synthase (ADCS) whereby chorismate and L-glutamine is converted to … aminodeoxychorismate and L-glutamic acid. The second reaction in the pABA branch is catalyzed by

Matched Description: receptors and beta2-adrenergic receptors. Blocking of beta1-adrenergic receptors in heart and vascular … smooth muscle can lead to reduced heart rate, cardiac output, and decreased blood pressure. Blocking

Matched Description: cells and binds to the 30S ribosomal subunit. By binding to 30S subunit which prevents tRNA binding to … mRNA ribosome complex and disrupting protein synthesis. Milk and dairy products should be avoided

Matched Description: Lomefloxacin is a fluoroquinolone used to prevent and treat a wide variety of infections in the … body. Lomefloxacin inhibits DNA gyrase (topoisomerase II) and topoisomerase IV. These proteins prevent … supercoiling in bacterial DNA. The inhibition of DNA gyrase (topoisomerase II) and topoisomerase IV

Matched Description: receptors, OP3. Propoxyphene binding to OP3 causes GTP exchange for GDP and inhibit adenylate cyclase … such as: substance P, GABA, dopamine, acetylcholine and noradrenaline. Opioids inhibit vasopressin … , somatostatin, insulin and glucagon release. Propoxyphene also causes the closure of voltage-gated … calcium channels and opens potassium channels causing the hyperpolarization of the membrane and

Matched Description: Celiprolol is a selective beta-1 adrenergic receptor antagonist and a beta-2 adrenergic receptor … partial agonist that is used for the management of hypertension and angina pectoris. The beta-2 … adrenergic receptor agonist activity is attributed to this effect, by causing vasodilation and lowering … blood pressure in hypertensive patients at rest and on exercise. The effects on heart rate and … of stress such as exercise, celiprolol attenuates chronotropic and inotropic responses to sympathetic

Matched Description: Solriamfetol, also known as Sunosi, is a dopamine and norepinephrine reuptake inhibitor (DNRI … and norepinephrine transporters but not serotonin transporters. Those transporters are called sodium … -dependent dopamine transporter and sodium-dependent noradrenaline transporter. This makes more … dopamine and noradrenaline available in the synapses of the brain. In consequence, the postsynaptic has … more of those neurotransmitters available. Norepinephrine and dopamine are important neurotransmitters

Matched Description: Alfentanil is used to induce and maintain anesthesia, as well as an analgesic. Alfentanil is a … short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak … analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during … surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically … cord, and other tissues. In clinical settings, alfentanil exerts its principal pharmacologic effects

Matched Description: Ritodrine is a adrenergic beta agonist used for the treatment and prophylaxis of premature labour … , increases cAMP level and decreases intracellular calcium concentration. The decrease of calcium … concentration leads to a relaxation of uterine smooth muscle and, therefore, a decrease in premature uterine … administered and it binds to the beta-2 adrenergic receptor, the G protein signalling cascade begins … . The alpha and beta/gamma subunits of the G protein separate and GDP is replaced with GTP on the

Matched Description: Orciprenaline is a beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD. This … then further stimulates intracellular adenylyl cyclase. Once Orciprenaline is administered and it … binds to the beta-2 adrenergic receptor, the G protein signalling cascade begins. The alpha and beta … /gamma subunits of the G protein separate and GDP is replaced with GTP on the alpha subunit. This alpha … kinase A (PKA) which in turn phosphorylates targets and inhibits MLCK through decreased calcium levels