SMP0002102
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Acetate Metabolism
Escherichia coli
Matched Description: acetyltransferase resulting in the release of a coenzyme A and an acetyl phosphate. The latter compound in … turn reacts with ADP through an acetate kinase resulting in the release of an ATP and an acetate … . The acetate reacts with ATP and coenzyme A through an acetyl-CoA synthase resulting in the release of … a diphosphate, an AMP and an acetyl-CoA.
Acetyl-CoA can be biosynthesized by acetoacetate reacting … with an acetyl-CoA through an acetoacetyl-CoA transferase resulting in the release of an acetate and
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SMP0000490
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Segawa Syndrome
Homo sapiens
Matched Description: Segawa syndrome is a condition in which the affected individual has a clumsy or unusual gait, and … experiences involuntary muscle contractions and uncontrolled movements (dystonia). Some cases are … mild, while others can be severe. The beginning signs of this condition are dystonia in the legs, and … important compound in the production of neurotransmitters, specifically dopamine and serotonin, and the … Segawa syndrome experience movement problems and an unusual gait.
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SMP0000497
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Tyrosine Hydroxylase Deficiency
Homo sapiens
Matched Description: Tyrosine Hydroxylase (TH) Deficiency is a rare inborn error of metabolism (IEM) and autosomal … production of catecholamines such as dopamine, norepinephrine and epinephrine are all essential for normal … nervous system function. Dopamine transmits signals to help the brain control physical movement and … emotional behavior. Norepinephrine and epinephrine are involved in the autonomic nervous system … body produces less dopamine, norepinephrine and epinephrine. Symptoms of the disorder include
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SMP0123231
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Lymecycline Anti-Bacterial Action Pathway
Homo sapiens
Matched Description: treatment of acne and other bacterial infections. Lymecycline is administered orally or intramuscular … /intravenous and travels through the blood stream to the site of infection where it inhibits the … bacteriostatic actions on intracellular and extracellular bacteria, treating susceptible bacterial infections.9 … It has been shown to be safe and effective in the treatment of moderate to severe acne. A caution … when using is that lymecycline may cause esophageal irritation and ulceration. This can be prevented
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SMP0126751
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Telithromycin Action Pathway
Homo sapiens
Matched Description: . Telithromycin is metabolized in the liver by cytochrome P450 and 3A4 enzymes. Telithromycin penetrates the … bacterial cell wall and acts on the ribosomal subunits to interfere with protein synthesis. These … elongation of the bacterial ribosome. Telithromycin binds to domains II and V of the 23S RNA of the … and this may even kill the bacteria. Common side effects from taking Telithromycin include dizziness … , headache, and taste disturbances, with the chance of experiencing more adverse effects such as
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SMP0126440
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Argatroban Action Pathway
Homo sapiens
Matched Description: the formation of a clot. Argatroban is metabolized by the liver through hydroxylation and … aromatization. Commonly administered through intravenous injection with a half-life of 30 - 60 minutes and is … primarily excreted through the feces, bile and urine. It can interact with food products so it is … best to avoid herbs and supplements with anticoagulant and antiplatelet activity such as garlic … , ginger, bilberry, danshen, piracetam and ginkgo biloba. Extreme caution with grapefruit products as
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SMP0126797
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Etorphine Opioid Agonist Action Pathway
Homo sapiens
Matched Description: cousin of morphine, and it is 40,000 times more powerful than morphine.
Etorphine binds to mu, delta … , and kappa opioid receptors, stimulating the exchange of GTP for GDP on the G-protein complex. As the … effector system is adenylate cyclase and cAMP located at the inner surface of the plasma membrane … channels and open calcium-dependent inwardly rectifying potassium channels. This results in … hyperpolarization and reduced neuronal excitability. Morphine acts at A delta and C pain fibres in the
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SMP0355441
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Acetate Metabolism
Brachyspira pilosicoli B2904
Matched Description: acetyltransferase resulting in the release of a coenzyme A and an acetyl phosphate. The latter compound in … turn reacts with ADP through an acetate kinase resulting in the release of an ATP and an acetate … . The acetate reacts with ATP and coenzyme A through an acetyl-CoA synthase resulting in the release of … a diphosphate, an AMP and an acetyl-CoA.
Acetyl-CoA can be biosynthesized by acetoacetate reacting … with an acetyl-CoA through an acetoacetyl-CoA transferase resulting in the release of an acetate and
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SMP0355434
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Acetate Metabolism
Grimontia hollisae CIP 101886
Matched Description: acetyltransferase resulting in the release of a coenzyme A and an acetyl phosphate. The latter compound in … turn reacts with ADP through an acetate kinase resulting in the release of an ATP and an acetate … . The acetate reacts with ATP and coenzyme A through an acetyl-CoA synthase resulting in the release of … a diphosphate, an AMP and an acetyl-CoA.
Acetyl-CoA can be biosynthesized by acetoacetate reacting … with an acetyl-CoA through an acetoacetyl-CoA transferase resulting in the release of an acetate and
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SMP0355403
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Acetate Metabolism
Hafnia alvei ATCC 51873
Matched Description: acetyltransferase resulting in the release of a coenzyme A and an acetyl phosphate. The latter compound in … turn reacts with ADP through an acetate kinase resulting in the release of an ATP and an acetate … . The acetate reacts with ATP and coenzyme A through an acetyl-CoA synthase resulting in the release of … a diphosphate, an AMP and an acetyl-CoA.
Acetyl-CoA can be biosynthesized by acetoacetate reacting … with an acetyl-CoA through an acetoacetyl-CoA transferase resulting in the release of an acetate and
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