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Matched Description: : dihydroergocornine, dihydroergocristine, and dihydroergocryptine. All these components are produced by the … fungus Claviceps purpurea and are all derivatives of the tetracyclic compound 6-methylergonovine … partial agonism/antagonism of adrenergic, dopaminergic and serotonergic receptors. The pharmacological

Matched Description: targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced … by the body, but also many medications like beta blockers, beta-2 (β2) agonists and alpha-2 (α2 … ) agonists, which are used to treat high blood pressure and asthma, for example. The α2, on the other … heterotrimeric G protein, composed of three subunits: a Gα protein such as Giα, and a complex of two … tightly linked proteins called Gβ and Gγ in a Gβγ complex. When not stimulated by a receptor, Gα is

Matched Description: encoding a reductase enzyme, and from there a chain reaction of effects lead to the observed … breakdown of many several amino acids, such as phenylalanine, is reduced and as a result their levels … include: dysphagia, global development delay, microcephaly, and intellectual disability (among

Matched Description: Lennox-Gastaut Syndrome (LGS). Rufinamide is a triazole derivative and an anticonvulsant medication to … effects on the voltage-dependence of gating and the time course of inactivation in some sodium channel … vomiting, headache, fatigue, and dizziness. Rufinamide is administered as an oral tablet or suspension.

Matched Description: Inositol 1,4,5-trisphosphate (IP3) and Diacylglycerol (DAG). Because of the inhibition, IP3 doesn't … activate the release of calcium from the sarcoplasmic reticulum, and DAG doesn't activate the … in the cytosol, and it, therefore, cannot bind to calmodulin.Calcium bound calmodulin is required for

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.

Matched Description: , galactose-1-phosphate uridylyltransferase and UDP-glucose 4-epimerase. Beta-D-galactose can be uptaken … degradation involving a lactose permease to uptake lactose from the environment and a beta-galactosidase … lactose interacts with water through a beta-galactosidase resulting in a beta-D-glucose and beta-D … -D-glucose 1-phosphate) interacts with UTP and a hydrogen ion in order to produce a uridine … output a glucose-1-phosphate and a uridine diphosphate galactose. The glucose -1-phosphate is