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Matched Description: and has both structural and signalling roles. In eukaryotes, there exist two phosphatidylcholine … biosynthesis pathways: the Kennedy pathway and the methylation pathway. The Kennedy pathway begins … -choline and subsequently phosphatidylcholine. It is the major synthesis route in animals. The

Matched Description: and has both structural and signalling roles. In eukaryotes, there exist two phosphatidylcholine … biosynthesis pathways: the Kennedy pathway and the methylation pathway. The Kennedy pathway begins … -choline and subsequently phosphatidylcholine. It is the major synthesis route in animals. The

Matched Description: and has both structural and signalling roles. In eukaryotes, there exist two phosphatidylcholine … biosynthesis pathways: the Kennedy pathway and the methylation pathway. The Kennedy pathway begins … -choline and subsequently phosphatidylcholine. It is the major synthesis route in animals. The

Matched Description: and a first generation typical antipsychotic. Based upon animal studies, mesoridazine, as with other

Matched Description: nucleus and binds to DNA bases. It preferentially binds to guanine but can also bind to adenine bases … . It's used for treated testicular cancer, ovarian cancer and other solid tumors and it targets all … to the site of the tumor. Cisplatin can cause nephrotoxicity due to ROS generation as well as nausea and vomiting.

Matched Description: conjunction with diet and exercise to improve glycemic control in patients. Inhibition of DPP-4 by … (PKA) and Rap guanine nucleotide exchange factor 4 (EPAC2). PKA inhibits the ATP-sensitive potassium … reticulum and into the cytosol. The high concentration of calcium ions in the cytosol triggers … biosynthesis, increase beta cell proliferation, decrease beta cell apoptosis and decrease glucagon secretion since these are also effects mediated by GLP-1.

Matched Description: , Candida glabrata, Candida parapsilosis, Candida tropicalis, and Cryptococcus neoformans. Each of these … the reaction of lanosterol with 3 oxygen and 3 NADPH to become 4,4-Dimethylcholesta-8,14,24-trienol … with byproducts of formic acid, 4 hydrogen ions, 4 water, and 3 NADP+. This reaction is the first … process inhibited by Fluconazole, the fungal cell cannot produce more fungi cells, and cannot keep the integrity of its own cell.

Matched Description: and has both structural and signalling roles. In eukaryotes, there exist two phosphatidylcholine … biosynthesis pathways: the Kennedy pathway and the methylation pathway. The Kennedy pathway begins … -choline and subsequently phosphatidylcholine. It is the major synthesis route in animals. The

Matched Description: subtypes, D1 through D5. D1 and D5 couple to Gs/olf and activate adenylyl cyclase, whereas D2, D3, and … D4 couple to Gi/o and inhibit it. Most GPCRs upon activation by an agonist are phosphorylated by … with GPCR only after stimulation with a ligand. G proteins have three subunits (α,β, and γ). When … a GPCR is activated, it induces the α subunit to release GDP and instead binds to guanosine … . The α subunit of G protein has a GTPase activity, and once it hydrolyzes GTP to GDP, it becomes

Matched Description: and has both structural and signalling roles. In eukaryotes, there exist two phosphatidylcholine … biosynthesis pathways: the Kennedy pathway and the methylation pathway. The Kennedy pathway begins … -choline and subsequently phosphatidylcholine. It is the major synthesis route in animals. The