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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 268757 results

SMP0130470

Pw132089 View Pathway
Metabolite

Plasminogen

Mus musculus

  • Matched Description: that degrades fibrin clots. In addition to its binding and activation on fibrin clots, PLG also … present in humans - type I plasminogen contains two glycosylation moieties (N-linked to N289 and O … , including tissue plasminogen activator (tPA), urokinase plasminogen activator (uPA), kallikrein, and … urokinase plasminogen activator. The conversion of plasminogen to plasmin involves the cleavage of the peptide bond between Arg-561 and Val-562.

  • Physiological

    SMP0000425

    Pw000427 View Pathway
    Metabolite

    Escitalopram Action Pathway

    Homo sapiens

  • Matched Description: concentrations of serotonin in the synaptic cleft and reverses the state of low concentration seen in … ). CREB-1 enters the nucleus and affects transcription of brain-derived neurotrophic factor (BDNF). BDNF

  • Drug Action

    SMP0121098

    Pw122368 View Pathway
    Metabolite

    Irinotecan Metabolism

    Bos taurus

  • Matched Description: Irinotecan, branded as Camptosar, Campto, Onivyde and others, is a cancer medication used to treat … colon and small cell lung cancers, alone or with other drugs. Irinotecan can be processed by the

  • Metabolic

    SMP0124685

    Pw126170 View Pathway
    Metabolite

    Sildenafil Action Pathway

    Homo sapiens

  • Matched Description: . Sexual stimulation causes the release of nitric oxide (NO) from nerves and endothelial cells into the … concentration of cGMP, increasing the vasodilation and improving blood flow leading to penile erection.

  • Drug Action

    SMP0125222

    Pw126764 View Pathway
    Metabolite

    Fentanyl Metabolism

    Homo sapiens

  • Matched Description: predicted by biotransformer to be metabolized into Hydroxyfentanyl by Cytochrome P450 1A2 and that … through bile to the intestines. 75% is excreted in the urine and 9% is excreted fecally. >7% is

  • Metabolic

    SMP0127076

    Pw128695 View Pathway
    Metabolite

    Histamine Neurological Sleep Pathway

    Rattus norvegicus

  • Matched Description: H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are … , allergic conjunctivitis, and urticaria. Wakefulness is regulated by histamine in the tuberomammillary

  • Physiological

    SMP0000646

    Pw000622 View Pathway
    Metabolite

    Fluoxetine Metabolism Pathway

    Homo sapiens

  • Matched Description: concentrations of serotonin in the synaptic cleft and reverses the state of low concentration seen in … -1 enters the nucleus and affects transcription of brain-derived neurotrophic factor (BDNF). BDNF

  • Drug Metabolism

    SMP0122246

    Pw123554 View Pathway
    Metabolite

    Methylglyoxal Degradation IV

    Pseudomonas aeruginosa

  • Matched Description: with the cofactor NADH, catalyzed by 2,5-diketo-D-gluconic acid reductase subunits A and B … used in glycolysis and pyruvate dehydrogenase pathways.

  • Metabolic

    SMP0108214

    Pw109256 View Pathway
    Protein

    Corticotropin Activation of Cortisol Production

    Rattus norvegicus

  • Matched Description: -lipotropin, melanocyte-stimulating hormone (MSH), and β-endorphin. As an essential component of the … activates pKA (protein kinase A) which phosphorylates downstream effectors that lead to androgen and cortisol production.

  • Protein/Peptide Hormone-Mediated
    Stress-Activated Signaling
    Neurological Signaling
    Kinase Signaling
    Cellular Response

    SMP0126062

    Pw127638 View Pathway
    Metabolite

    Peramivir Action Pathway

    Homo sapiens

  • Matched Description: A and B. Being a specific influenza virus neuraminidase inhibitor, peramivir works by preventing … , peramivir causes viruses to aggregate and fail to be released from the cell surface. This drug has

  • Drug Action