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Matched Description: and has both structural and signalling roles. In eukaryotes, there exist two phosphatidylcholine … biosynthesis pathways: the Kennedy pathway and the methylation pathway. The Kennedy pathway begins … -choline and subsequently phosphatidylcholine. It is the major synthesis route in animals. In the … diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and

Matched Description: and has both structural and signalling roles. In eukaryotes, there exist two phosphatidylcholine … biosynthesis pathways: the Kennedy pathway and the methylation pathway. The Kennedy pathway begins … -choline and subsequently phosphatidylcholine. It is the major synthesis route in animals. In the … diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and

Matched Description: and has both structural and signalling roles. In eukaryotes, there exist two phosphatidylcholine … biosynthesis pathways: the Kennedy pathway and the methylation pathway. The Kennedy pathway begins … -choline and subsequently phosphatidylcholine. It is the major synthesis route in animals. In the … diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and

Matched Description: pancreatic beta cells, and increasing the sensitivity of peripheral tissues to insulin. Gliquidone binds … and inhibits the ATP-sensitive potassium channel receptors ( ATP-binding cassette sub-family C member … 8) on the pancreatic cell surface, reducing potassium conductance and causing the depolarization of … -sensitive calcium channels. This action increases the intracellular calcium ion concentration and … sulfonylurea receptor (SUR) and the second one which is the inwardly rectifying K+ channel (kir6.x

Matched Description: anticholinergic and calcium-modulating properties. The efferent connection of the pelvic nerve is … muscle. Propiverine blocks calcium ion influx and modulates the intracellular calcium in urinary … detrusor muscle, and antimuscarinics such as propiverine exert their effects by competitively … inhibiting the binding of acetylcholine at muscarinic receptors on detrusor smooth muscle cells and other … the bladder. Therefore, muscarinic receptor-2 may highly contribute to the relatively selective and

Matched Description: and as a treatment for extrapyramidal symptoms caused by drugs affecting the central nervous system … higher affinity for central muscarinic receptors located in the cerebral cortex and lower affinity for … innervated by the parasympathetic system, such as the salivary glands, eyes, and smooth muscles … (directly and indirectly), are affected, even at smaller doses. Possible side effects of using … Trihexyphenidyl may include dry mouth, constipation, nausea, and vomiting. Trihexyphenidyl is administered as an oral tablet.

Matched Description: treatment of acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute … microtubules induces two proteins; cellular tumor antigen p53 and cyclin-dependent kinase inhibitor … former protein, p53, acts on BAK and BAX to enact conformational changes, creating pores in the … cell, which cleave essential cellular proteins. In this way, p53 and p21 work alongside each other … to promote apoptosis and terminate unhealthy cells. Vindesine is especially valuable as a drug

Matched Description: starts with acetyl-CoA and butyryl-CoA, a coenzyme A activated form of butyric acid, a 4-carbon fatty … , tetradecanoyl-CoA and finally the 16 carbon hexadecanoyl-CoA. Finally, hexadecanoyl is transported out of … the mitochondrion and into the lysosome, where palmitoyl-protein thioesterase 1 catalyzes its … reversible reaction with a water molecule that removes the CoA group and forms palmitic acid. Palmitic acid … is the final product of this pathway, and it is involved in the fatty acid degradation pathway.

Matched Description: fibrillation/flutter and ventricular arrhythmias. It can be found under the brand name Rhythmol. Used to … monophasic action potential. In Purkinje fibers, and to a lesser extent myocardial fibers … antiarrhythmic actions. Diastolic excitability threshold is increased and effective refractory period … prolonged. Propafenone reduces spontaneous automaticity and depresses triggered activity. At very high … administered as an oral tablet. Some side effects of using propafenone may include dizziness, dry mouth, headache, and nausea.

Matched Description: Escherichia coli can utilize D-mannose for its sole carbon and energy source. Alpha-D-mannose is … isomerase. D-fructose-6-phosphate is an intermediate of glycolysis and can enter the pathways of … phosphorylated aldohexoses (β-D-glucose-6-phosphate, D-mannose-6-phosphate) and phosphorylated ketohexoses (D … phosphomannomutase and mannose-1-phosphate guanylyltransferase. GDP-D-mannose produces GDP-L-fucose beginning … epimerase and reductase of GDP-4-dehydro-6-deoxy-D-mannose. L-fucose then enters the colanic acid building blocks biosynthesis pathway.