Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
Loader

Browsing Search Results

Filter by Species:

Filter by Pathway Type:

Select Pathway Sub-Category:

Select Pathway Sub-Category:

Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 518708 results

SMP0000193

Pw000219 View Pathway
Metabolite

Iminoglycinuria

Homo sapiens

  • Matched Description: acid transporter which facilitates the reuptake of glycine, proline, and hydroxyproline. This … disorder is characterized by a large accumulation of glycine, proline, and hydroxyproline in the urine … . Symptoms of the disorder include urolithiasis and mental retardation.

  • Matched Compounds: Aldosterone

  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Solute carrier family 6 member 20 … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Disease

    SMP0000081

    Pw000327 View Pathway
    Metabolite

    Methyclothiazide Action Pathway

    Homo sapiens

  • Matched Description: chloride and sodium from lumen to epithelial cell, and sodium/potassium ATPases facilitate the

  • Matched Compounds: Aldosterone

  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Solute carrier family 6 member 20 … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000105

    Pw000334 View Pathway
    Metabolite

    Metolazone Action Pathway (old)

    Homo sapiens

  • Matched Description: chloride and sodium from lumen to epithelial cell, and sodium/potassium ATPases facilitate the export of

  • Matched Compounds: Aldosterone

  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Solute carrier family 6 member 20 … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000121

    Pw000339 View Pathway
    Metabolite

    Trichlormethiazide Action Pathway

    Homo sapiens

  • Matched Description: called thiazides. Thiazides and thiazide-like drugs are diuretics commonly employed to control … hypertension. Trichloromethiazide acts by inhibiting chloride and potentially sodium reabsorption in the … increased fluid loss which ultimately reduces blood volume and pressure. Trichlormethiazide also acts … to inhibit sodium uptake and increase potassium excretion which also serves to increase fluid loss … . The long-term antihypertensive effects of thiazides and thiazide-like drugs such as

  • Matched Compounds: Aldosterone

  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Solute carrier family 6 member 20 … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000132

    Pw000341 View Pathway
    Metabolite

    Triamterene Action Pathway

    Homo sapiens

  • Matched Description: used to manage hypertension and edema. It acts by blocking epithelial sodium channels in the late … in the nephron. This primarily contributes to an increase in sodium excretion and consequentially … , fluid excretion which decreases blood volume and blood pressure. Potassium secretion is indirectly … action for potassium-sparing drugs -- and has the potential to induce hyperkalemia which can potentially lead to severe heart arrhythmias.

  • Matched Compounds: Aldosterone

  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Solute carrier family 6 member 20 … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000088

    Pw000328 View Pathway
    Metabolite

    Bumetanide Action Pathway

    Homo sapiens

  • Matched Description: hypertonic and a decreased osmotic gradient thereby reducing the water reabsorption. In the nephron, the … think ascending limb reabsorbs 25% of sodium and is a good target for diuretics.

  • Matched Compounds: Aldosterone

  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Solute carrier family 6 member 20 … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000091

    Pw000330 View Pathway
    Metabolite

    Quinethazone Action Pathway (old)

    Homo sapiens

  • Matched Description: molecule that belongs to a class of drugs called thiazides. Thiazides and thiazide-like drugs are diuretics … the nephron and therefore increase fluid loss which decreases extracellular fluid (ECF), plasma … volume, and ultimately blood pressure. In the case of quinethazone, it inhibits the sodium-chloride … long-term mechanism of action isn’t as well-characterized and it is thought that other processes … beyond regulating plasma and ECF volumes are involved as these two volumes return to baseline within 4-6 weeks of first use of thiazides.

  • Matched Compounds: Aldosterone

  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Solute carrier family 6 member 20 … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000108

    Pw000335 View Pathway
    Metabolite

    Hydroflumethiazide Action Pathway

    Homo sapiens

  • Matched Description: chloride and sodium from lumen to epithelial cell, and sodium/potassium ATPases facilitate the export

  • Matched Compounds: Aldosterone

  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Solute carrier family 6 member 20 … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000133

    Pw000342 View Pathway
    Metabolite

    Amiloride Action Pathway

    Homo sapiens

  • Matched Description: Amiloride is a diuretic that inhibits the sodium channels in the late distal convoluted tubule and … reabsorption results in increased osmolarity in the lumen and decreased osmolarity in the interstitium … electrochemical gradient and therefore, inhibits potassium excretion. Amiloride causes an increase in … sodium excretion and a decrease in potassium secretion. The drug is typically prescribed to patients with depleted potassium.

  • Matched Compounds: Aldosterone

  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Solute carrier family 6 member 20 … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000184

    Pw000216 View Pathway
    Metabolite

    Glucose Transporter Defect (SGLT2)

    Homo sapiens

  • Matched Description: responsible for approximately 90% of the kidney's reabsorption of glucose, and can be found in the S1 … kidney. There are some drugs that inhibit SGLT2 and are used to decrease blood sugar in patients with type 2 diabetes mellitus.

  • Matched Compounds: Aldosterone

  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Solute carrier family 6 member 20 … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Disease