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Matched Description: lipoproteins, peptidoglycans, lipotechoic acids, and mannan. TLR3 recognizes viral double-stranded … RNA, small interfering RNAsa, and self-RNAs. TLR4 recognizes lipopolysaccharides. TLR7 recognizes … single-stranded RNA. TLR9 recognizes bacterial and viral DNA with unmethylated CpG-DNA motifs. TLRs … are synthesized in the endoplasmic reticulum, moved to the Golgi, and then recruited to the cell … . MYD88 is recruited by all TLRs. Adaptor TIRAP recruits MYD88 to cell surface TLRs, including TLR2 and

Matched Proteins: TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

Matched Description: of GSD-III is higher in North African Jews (1 in 5 400), Faroese (1 in 3 100) and the Inuit … is structurally abnormal and impairs the function of certain organs and tissues, especially the … liver and muscles. GSD III typically presents during infancy with hypoglycemia and failure to thrive … . Clinical examination usually reveals hepatomegaly. Muscular disease, including hypotonia and … cardiomyopathy, usually occurs later in life. GSD III is divided into the types IIIa, IIIb, IIIc, and IIId

Matched Description: human immunodeficiency virus (HIV) infection. Lopinavir is marketed and administered exclusively in … bioavailability and extensive biotransformation. The HIV virus binds and penetrates the host cell. Viral RNA … is transcribed into viral DNA via reverse transcriptase. Viral DNA enters the host nucleus and is … polyprotein, where Gag encodes for the capsid and matrix protein to form the outer protein shell, and … Pol encodes for the reverse transcriptase and integrase protein to synthesize and incorporate its

Matched Description: Asthmanefrin and is orally inhaled to act on both alpha and beta adrenergic receptors. This drug has a … rapid onset and short duration and acts as a smooth muscle relaxant and constrictor in different … to relax the smooth muscle of the lungs, and it is also an alpha-1 adrenergic receptor agonist which … the hydrostatic pressure and consequently bronchial mucosal edema. Racepinephrine is a racemic … mixture consisting of d-Epinephrine and l-Epinephrine enantiomers. Epinephrine is a non-selective α- and β

Matched Description: Acepromazine is a phenothiazine tranquilizer that blocks dopamine receptors in the CNS and … in animals as a sedative and antiemetic. Its principal value is in quietening and calming anxious … dopaminergic-receptors (subtypes D1, D2, D3 and D4 - different antipsychotic properties on … productive and unproductive symptoms), on serotonergic-receptors (5-HT1 and 5-HT2, with anxiolytic … , antidepressive and antiaggressive properties as well as an attenuation of extrapyramidal side-effects, but

Matched Description: of GSD-III is higher in North African Jews (1 in 5 400), Faroese (1 in 3 100) and the Inuit … is structurally abnormal and impairs the function of certain organs and tissues, especially the … liver and muscles. GSD III typically presents during infancy with hypoglycemia and failure to thrive … . Clinical examination usually reveals hepatomegaly. Muscular disease, including hypotonia and … cardiomyopathy, usually occurs later in life. GSD III is divided into the types IIIa, IIIb, IIIc, and IIId

Matched Description: ) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Finafloxacin inhibits DNA … gyrase (topoisomerase II) and topoisomerase IV. These proteins prevent supercoiling in bacterial … DNA. The inhibition of DNA gyrase (topoisomerase II) and topoisomerase IV causes supercoiling of the bacterial DNA. This prevents DNA replication.

Matched Description: Pseudouridine is phosphorylated by interacting with atp and a psuK resulting in the release of an … ADP, a hydrogen ion and a pseudouridine 5'-phosphate. The latter compound then reacts with water … through a pseudouridine 5'-phosphate glycosidase resulting in the release of a uracil and D-ribofuranose 5-phosphate

Matched Description: Pseudouridine is phosphorylated by interacting with atp and a psuK resulting in the release of an … ADP, a hydrogen ion and a pseudouridine 5'-phosphate. The latter compound then reacts with water … through a pseudouridine 5'-phosphate glycosidase resulting in the release of a uracil and D-ribofuranose 5-phosphate

Matched Description: Pseudouridine is phosphorylated by interacting with atp and a psuK resulting in the release of an … ADP, a hydrogen ion and a pseudouridine 5'-phosphate. The latter compound then reacts with water … through a pseudouridine 5'-phosphate glycosidase resulting in the release of a uracil and D-ribofuranose 5-phosphate