SMP0423892
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Phenylalanine Metabolism
Neisseria elongata subsp. glycolytica ATCC 29315
Matched Description: through the same previous enzyme resulting in a release of carbon dioxide, water and a phenolpyruvic … acid. Three enzymes those enconde by tyrB, aspC and ilvE are involved in catalyzing the third step of … these pathways, all three can contribute to the synthesis of phenylalanine: only tyrB and aspC … with ammonia, a reduced acceptor and a D-amino acid dehydrogenase, resulting in a water, an … acceptor and a D-phenylalanine, which can be then transported into the periplasmic space by aromatic amino
Matched Compound Synonyms: 2-oxo-3-phenylpropanoic acid (mixture oxo and keto) … 2-oxo-3-phenylpropanoic acid (mixture oxo and keto) … Ammonia (conc 20% or greater)
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SMP0030880
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Estrone Metabolism
Homo sapiens
Matched Description: Estrone (also known as oestrone) is a weak endogenous estrogen, a steroid and minor female sex … hormone. Estrone is synthesized from cholesterol and secreted from gonads. Endoplasmic reticulum (ER) is … the place that estrone undergoes primary metabolism. Estrone sulfate and estrone glucuronide are … the conjugated product of estrone; and CYP450 can hydroxylate estrone into catechol estrogens. The
Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD
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SMP0124000
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Acylcarnitine 12-hydroxydodecanoylcarnitine
Homo sapiens
Matched Description: transport acyl-groups, organic acids and fatty acids, from the cytoplasm into the mitochondria so that they … compounds such as carnitine (to form acylcarnitines) and amino acids (to form acyl amides). The carnitine … 2 enzyme found in the mitochondrial inner membrane to once again form 12-hydroxydodecanoyl-CoA and L … in both directions, and L-acetylcarnitine and CoA can react to form acetyl-CoA and L-carnitine in … preventing 12-hydroxydodecanoylcarnitine from forming and thereby preventing it from being transported into the mitochondria.
Matched Protein Synonyms: Solute carrier family 25 member 20
Matched Compound Synonyms: Omega-oh dodecanoic acid … Omega-oh lauric acid … Omega-oh dodecanoate … Omega-oh laate … Omega-oh laic acid
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SMP0126393
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Amifampridine Action Pathway
Homo sapiens
Matched Description: , and posttetanic potentiation in addition to autonomic dysfunction. This drug blocks presynaptic fast … voltage-gated potassium channels, which prolongs the action potential and increases presynaptic … . Increased intracellular calcium enhances the exocytosis of acetylcholine-containing vesicles and
Matched Compound Synonyms: channels, and subsequently prolongs the action potential and increases presynaptic calcium … concentrations. it is currently used as the first-line symptomatic treatment for lems in adult patients and is … channels, and subsequently prolongs the action potential and increases presynaptic calcium … concentrations. it is currently used as the first-line symptomatic treatment for lems in adult patients and is … channels, and subsequently prolongs the action potential and increases presynaptic calcium
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SMP0099954
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Cardiolipin Biosynthesis CL(20:0/20:1(11Z)/22:0/22:1(13Z))
Drosophila melanogaster
Matched Description: about 20% of the total lipid composition. It is essential for the optimal function of numerous … synthesizes phosphatidylglycerophosphate (PGP). Sixth, phosphatidylglycerophosphatase and protein
Matched Compounds: LPA(20:0/0:0) … PA(20:0/20:1(11Z)) … CDP-DG(20:0/20:1(11Z)) … PGP(20:0/20:1(11Z)) … PG(20:0/20:1(11Z))
Matched Compound Synonyms: Coa(20:0) … Pa(20:0/0:0) … Coa(20:1(11z)) … Pa(20:0/20:1) … Pa(20:0/20:1n9)
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SMP0082185
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Cardiolipin Biosynthesis CL(20:0/20:1(11Z)/22:0/22:0)
Arabidopsis thaliana
Matched Description: Cardiolipin (CL) is an important component of the inner mitochondrial membrane, and it is essential … (PGP). Sixth, phosphatidylglycerophosphatase and protein-tyrosine phosphatase dephosphorylates PGP to
Matched Compounds: LPA(20:0/0:0) … PA(20:0/20:1(11Z)) … CDP-DG(20:0/20:1(11Z)) … PGP(20:0/20:1(11Z)) … PG(20:0/20:1(11Z))
Matched Compound Synonyms: Coa(20:0) … Pa(20:0/0:0) … Coa(20:1(11z)) … Pa(20:0/20:1) … Pa(20:0/20:1n9)
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SMP0086723
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Cardiolipin Biosynthesis CL(20:4(5Z,8Z,11Z,14Z)/20:4(8Z,11Z,14Z,17Z)/20:5(5Z,8Z,11Z,14Z,17Z)/20:5(5Z,8Z,11Z,14Z,17Z))
Caenorhabditis elegans
Matched Description: about 20% of the total lipid composition. It is essential for the optimal function of numerous … synthesizes phosphatidylglycerophosphate (PGP). Sixth, phosphatidylglycerophosphatase and protein
Matched Compounds: LPA(20:4(5Z,8Z,11Z,14Z)/0:0) … PA(20:4(5Z,8Z,11Z,14Z)/20:4(8Z,11Z,14Z,17Z)) … CDP-DG(20:4(5Z,8Z,11Z,14Z)/20:4(8Z,11Z,14Z,17Z)) … PGP(20:4(5Z,8Z,11Z,14Z)/20:4(8Z,11Z,14Z,17Z)) … PG(20:4(5Z,8Z,11Z,14Z)/20:4(8Z,11Z,14Z,17Z))
Matched Compound Synonyms: Coa(20:4(5z,8z,11z,14z)) … Lysophosphatidic acid (20:4(5z,8z,11z,14z)/0:0) … Pa(20:4(5z,8z,11z,14z)/0:0) … Pa(20:4/0:0) … Pa(20:4/20:4)
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SMP0086716
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Cardiolipin Biosynthesis CL(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)/20:4(8Z,11Z,14Z,17Z))
Caenorhabditis elegans
Matched Description: about 20% of the total lipid composition. It is essential for the optimal function of numerous … synthesizes phosphatidylglycerophosphate (PGP). Sixth, phosphatidylglycerophosphatase and protein
Matched Compounds: LPA(20:4(5Z,8Z,11Z,14Z)/0:0) … PA(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) … CDP-DG(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) … PGP(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) … PG(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z))
Matched Compound Synonyms: Coa(20:4(5z,8z,11z,14z)) … Lysophosphatidic acid (20:4(5z,8z,11z,14z)/0:0) … Pa(20:4(5z,8z,11z,14z)/0:0) … Pa(20:4/0:0) … Pa(20:4/20:4)
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SMP0125664
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3-Methylglutaconic Aciduria Type I
Homo sapiens
Matched Description: , 3-methylglutaconic acid, and methylglutaric acid in urine. Symptoms include hypoglycemia, low … birth weight, coma, seizures, and mental retardation. Treatment includes a low protein diet.
Matched Protein Synonyms: Solute carrier family 25 member 20
Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [oh(oh)] … Carnipass 20
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SMP0082178
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Cardiolipin Biosynthesis CL(20:0/20:1(11Z)/20:1(11Z)/20:1(11Z))
Arabidopsis thaliana
Matched Description: Cardiolipin (CL) is an important component of the inner mitochondrial membrane, and it is essential … (PGP). Sixth, phosphatidylglycerophosphatase and protein-tyrosine phosphatase dephosphorylates PGP to
Matched Compounds: LPA(20:0/0:0) … PA(20:0/20:1(11Z)) … CDP-DG(20:0/20:1(11Z)) … PGP(20:0/20:1(11Z)) … PG(20:0/20:1(11Z))
Matched Compound Synonyms: Coa(20:0) … Pa(20:0/0:0) … Coa(20:1(11z)) … Pa(20:0/20:1) … Pa(20:0/20:1n9)
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