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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 512874 results

SMP0087238

Pw088257 View Pathway
Metabolite

Steroidogenesis

Bos taurus

  • Matched Description: , aldosterone and progesterone. To begin the synthesis of steroid hormones, cholesterol synthesizes a … the mitochondria and becoming fixed in the inner mitochondrial membrane. Once there, the cholesterol … aldosterone. 17alpha-hydroxyprogesterone is created from pregnenolone by using 3-beta-hydroxysteroid … active steroid hormone, and its conversion to the inactive cortisone has been known to occur in … pathway such as testosterone and estrogen. Cortisol receptors are found in almost every bodily cell, so
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Metabolic

    SMP0120868

    Pw122129 View Pathway
    Metabolite

    Apparent Mineralocorticoid Excess Syndrome

    Rattus norvegicus

  • Matched Description: , symptoms include low levels of aldosterone, failure to thrive and hypertension. Treatment with … corticoids that suppress the secretion of cortisol within the body can affect blood pressure and aldosterone … , is an extremely rare inborn error of metabolism (IEM) and autosomal recessive disorder of the … -beta-dehydrogenase isozyme 2, and enzyme that converts cortisol to cortisone in the cell. Without … tetrahydrocortisone levels dissipate. AME is characterized excessive thirst and urination, and along with this
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Disease

    SMP0120641

    Pw121897 View Pathway
    Metabolite

    Corticosterone Methyl Oxidase I Deficiency (CMO I)

    Mus musculus

  • Matched Description: aldosterone deficiency among other names, is a genetic disorder that is autosomally linked and … , also called aldosterone synthase, which is used to catalyze the conversion of 18-hydroxycorticosterone … to aldosterone. This leads to a decrease in the amount of aldosterone present in the cells, which is … deficiency, aldosterone levels are so low that they are undetectable in plasma.
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Disease

    SMP0120649

    Pw121905 View Pathway
    Metabolite

    Apparent Mineralocorticoid Excess Syndrome

    Mus musculus

  • Matched Description: , symptoms include low levels of aldosterone, failure to thrive and hypertension. Treatment with … corticoids that suppress the secretion of cortisol within the body can affect blood pressure and aldosterone … , is an extremely rare inborn error of metabolism (IEM) and autosomal recessive disorder of the … -beta-dehydrogenase isozyme 2, and enzyme that converts cortisol to cortisone in the cell. Without … tetrahydrocortisone levels dissipate. AME is characterized excessive thirst and urination, and along with this
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Disease

    SMP0063672

    Pw064653 View Pathway
    Metabolite

    Steroidogenesis

    Mus musculus

  • Matched Description: , aldosterone and progesterone. To begin the synthesis of steroid hormones, cholesterol synthesizes a … the mitochondria and becoming fixed in the inner mitochondrial membrane. Once there, the cholesterol … aldosterone. 17alpha-hydroxyprogesterone is created from pregnenolone by using 3-beta-hydroxysteroid … active steroid hormone, and its conversion to the inactive cortisone has been known to occur in … pathway such as testosterone and estrogen. Cortisol receptors are found in almost every bodily cell, so
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Metabolic

    SMP0120858

    Pw122119 View Pathway
    Metabolite

    11-beta-Hydroxylase Deficiency (CYP11B1)

    Rattus norvegicus

  • Matched Description: recessive disorder and caused by a defective 11-beta-hydroxylase. 11-beta-hydroxylase catalyzes the … conversion of cortexolone into cortisol which is useful for maintaining blood sugar levels and … endoplasmic reticulum (ER). Symptoms of the disorder include abnormality of hair growth rate and
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Disease

    SMP0120860

    Pw122121 View Pathway
    Metabolite

    Corticosterone Methyl Oxidase I Deficiency (CMO I)

    Rattus norvegicus

  • Matched Description: aldosterone deficiency among other names, is a genetic disorder that is autosomally linked and … , also called aldosterone synthase, which is used to catalyze the conversion of 18-hydroxycorticosterone … to aldosterone. This leads to a decrease in the amount of aldosterone present in the cells, which is … deficiency, aldosterone levels are so low that they are undetectable in plasma.
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Disease

    SMP0087331

    Pw088350 View Pathway
    Metabolite

    Steroidogenesis

    Rattus norvegicus

  • Matched Description: , aldosterone and progesterone. To begin the synthesis of steroid hormones, cholesterol synthesizes a … the mitochondria and becoming fixed in the inner mitochondrial membrane. Once there, the cholesterol … aldosterone. 17alpha-hydroxyprogesterone is created from pregnenolone by using 3-beta-hydroxysteroid … active steroid hormone, and its conversion to the inactive cortisone has been known to occur in … pathway such as testosterone and estrogen. Cortisol receptors are found in almost every bodily cell, so
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Metabolic

    SMP0120451

    Pw121702 View Pathway
    Metabolite

    Adrenal Hyperplasia Type 5 or Congenital Adrenal Hyperplasia Due to 17 alpha-Hydroxylase Deficiency

    Mus musculus

  • Matched Description: -Hydroxylase Deficiency is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of … cortisol and sex steroids synthesis caused by a defect in the CYP17A1 gene which codes for Steroid 17 … -alpha-hydroxylase/17,20 lyase. These 2 enzymes catalyze pregnenolone and progesterone to their 17 … -hydroxy forms in steroidogenesis and mediate three key transformations in cortisol and sex steroid … synthesis. This disorder is characterized by a decrease in both cortisol and sex steroids and increase
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Disease

    SMP0120470

    Pw121721 View Pathway
    Metabolite

    Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH

    Mus musculus

  • Matched Description: Congenital Lipoid Adrenal Hyperplasia (CLA),also called steroid 20-22 desmolase deficiency and … lipoid CAH, is an autosomal recessive disorder and caused by a defective cholesterol side-chain cleavage … disorder is not clear. Extra glucocorticoid and mineral replacement could be the potential treatments.
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Disease