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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 279582 results

SMP0120470

Pw121721 View Pathway
Metabolite

Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH

Mus musculus

  • Matched Description: Congenital Lipoid Adrenal Hyperplasia (CLA),also called steroid 20-22 desmolase deficiency and … lipoid CAH, is an autosomal recessive disorder and caused by a defective cholesterol side-chain cleavage … disorder is not clear. Extra glucocorticoid and mineral replacement could be the potential treatments.
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Disease

    SMP0120860

    Pw122121 View Pathway
    Metabolite

    Corticosterone Methyl Oxidase I Deficiency (CMO I)

    Rattus norvegicus

  • Matched Description: aldosterone deficiency among other names, is a genetic disorder that is autosomally linked and … , also called aldosterone synthase, which is used to catalyze the conversion of 18-hydroxycorticosterone … to aldosterone. This leads to a decrease in the amount of aldosterone present in the cells, which is … deficiency, aldosterone levels are so low that they are undetectable in plasma.
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Disease

    SMP0120858

    Pw122119 View Pathway
    Metabolite

    11-beta-Hydroxylase Deficiency (CYP11B1)

    Rattus norvegicus

  • Matched Description: recessive disorder and caused by a defective 11-beta-hydroxylase. 11-beta-hydroxylase catalyzes the … conversion of cortexolone into cortisol which is useful for maintaining blood sugar levels and … endoplasmic reticulum (ER). Symptoms of the disorder include abnormality of hair growth rate and
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Disease

    SMP0063672

    Pw064653 View Pathway
    Metabolite

    Steroidogenesis

    Mus musculus

  • Matched Description: , aldosterone and progesterone. To begin the synthesis of steroid hormones, cholesterol synthesizes a … the mitochondria and becoming fixed in the inner mitochondrial membrane. Once there, the cholesterol … aldosterone. 17alpha-hydroxyprogesterone is created from pregnenolone by using 3-beta-hydroxysteroid … active steroid hormone, and its conversion to the inactive cortisone has been known to occur in … pathway such as testosterone and estrogen. Cortisol receptors are found in almost every bodily cell, so
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Metabolic

    SMP0087331

    Pw088350 View Pathway
    Metabolite

    Steroidogenesis

    Rattus norvegicus

  • Matched Description: , aldosterone and progesterone. To begin the synthesis of steroid hormones, cholesterol synthesizes a … the mitochondria and becoming fixed in the inner mitochondrial membrane. Once there, the cholesterol … aldosterone. 17alpha-hydroxyprogesterone is created from pregnenolone by using 3-beta-hydroxysteroid … active steroid hormone, and its conversion to the inactive cortisone has been known to occur in … pathway such as testosterone and estrogen. Cortisol receptors are found in almost every bodily cell, so
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Metabolic

    SMP0120649

    Pw121905 View Pathway
    Metabolite

    Apparent Mineralocorticoid Excess Syndrome

    Mus musculus

  • Matched Description: , symptoms include low levels of aldosterone, failure to thrive and hypertension. Treatment with … corticoids that suppress the secretion of cortisol within the body can affect blood pressure and aldosterone … , is an extremely rare inborn error of metabolism (IEM) and autosomal recessive disorder of the … -beta-dehydrogenase isozyme 2, and enzyme that converts cortisol to cortisone in the cell. Without … tetrahydrocortisone levels dissipate. AME is characterized excessive thirst and urination, and along with this
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Disease

    SMP0120641

    Pw121897 View Pathway
    Metabolite

    Corticosterone Methyl Oxidase I Deficiency (CMO I)

    Mus musculus

  • Matched Description: aldosterone deficiency among other names, is a genetic disorder that is autosomally linked and … , also called aldosterone synthase, which is used to catalyze the conversion of 18-hydroxycorticosterone … to aldosterone. This leads to a decrease in the amount of aldosterone present in the cells, which is … deficiency, aldosterone levels are so low that they are undetectable in plasma.
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Disease

    SMP0120868

    Pw122129 View Pathway
    Metabolite

    Apparent Mineralocorticoid Excess Syndrome

    Rattus norvegicus

  • Matched Description: , symptoms include low levels of aldosterone, failure to thrive and hypertension. Treatment with … corticoids that suppress the secretion of cortisol within the body can affect blood pressure and aldosterone … , is an extremely rare inborn error of metabolism (IEM) and autosomal recessive disorder of the … -beta-dehydrogenase isozyme 2, and enzyme that converts cortisol to cortisone in the cell. Without … tetrahydrocortisone levels dissipate. AME is characterized excessive thirst and urination, and along with this
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Disease

    SMP0087238

    Pw088257 View Pathway
    Metabolite

    Steroidogenesis

    Bos taurus

  • Matched Description: , aldosterone and progesterone. To begin the synthesis of steroid hormones, cholesterol synthesizes a … the mitochondria and becoming fixed in the inner mitochondrial membrane. Once there, the cholesterol … aldosterone. 17alpha-hydroxyprogesterone is created from pregnenolone by using 3-beta-hydroxysteroid … active steroid hormone, and its conversion to the inactive cortisone has been known to occur in … pathway such as testosterone and estrogen. Cortisol receptors are found in almost every bodily cell, so
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Metabolic

    SMP0120690

    Pw121946 View Pathway
    Metabolite

    Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH

    Rattus norvegicus

  • Matched Description: Congenital Lipoid Adrenal Hyperplasia (CLA),also called steroid 20-22 desmolase deficiency and … lipoid CAH, is an autosomal recessive disorder and caused by a defective cholesterol side-chain cleavage … disorder is not clear. Extra glucocorticoid and mineral replacement could be the potential treatments.
  • Matched Compounds: 3a,11b,21-Trihydroxy-20-oxo-5b-pregnan-18-al … Aldosterone … 3a-Hydroxy-5b-pregnane-20-one
  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosteroneAldosterone … (3a,5b,11b)-3,11,21-trihydroxy-pregnan-20-one

  • Disease