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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 279126 results

SMP0120874

Pw122135 View Pathway
Metabolite

Cystinuria

Rattus norvegicus

  • Matched Description: in the kidneys. The mutations cause this process to be compromised and allows the amino acids to … build up and have a high concentration in urine. This causes crystals to form and become stones as they … , develop infection and disrupt the passing of urine through the urinary tract if the stones create a blockage there.
  • Matched Compounds: Aldosterone
  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT
  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

  • Disease

    SMP0119387

    Pw120610 View Pathway
    Metabolite

    Kidney Function

    Rattus norvegicus

  • Matched Description: angiotensin II and aldosterone, which increases sodium chloride reabsorption. This results in an … , nutrient reabsorption, and regulating electrolyte concentrations, acid-base balance, extracellular fluid … volume, and blood pressure. The early proximal tubule is where glucose, amino acids, sodium … , chlorine, phosphate, bicarbonate, and water are reabsorbed. Only water is reabsorbed in the thin descending … loop of Henle, while sodium, chlorine and potassium are reabsorbed in the thick ascending loop of
  • Matched Compounds: Aldosterone
  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT
  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

  • Physiological

    SMP0119367

    Pw120590 View Pathway
    Metabolite

    Kidney Function

    Mus musculus

  • Matched Description: angiotensin II and aldosterone, which increases sodium chloride reabsorption. This results in an … , nutrient reabsorption, and regulating electrolyte concentrations, acid-base balance, extracellular fluid … volume, and blood pressure. The early proximal tubule is where glucose, amino acids, sodium … , chlorine, phosphate, bicarbonate, and water are reabsorbed. Only water is reabsorbed in the thin descending … loop of Henle, while sodium, chlorine and potassium are reabsorbed in the thick ascending loop of
  • Matched Compounds: Aldosterone
  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3A … Neutral and basic amino acid transport protein rBAT
  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

  • Physiological

    SMP0120547

    Pw121803 View Pathway
    Metabolite

    Iminoglycinuria

    Mus musculus

  • Matched Description: acid transporter which facilitates the reuptake of glycine, proline, and hydroxyproline. This … disorder is characterized by a large accumulation of glycine, proline, and hydroxyproline in the urine … . Symptoms of the disorder include urolithiasis and mental retardation.
  • Matched Compounds: Aldosterone
  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3A … Neutral and basic amino acid transport protein rBAT
  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

  • Disease

    SMP0120483

    Pw121735 View Pathway
    Metabolite

    Glucose Transporter Defect (SGLT2)

    Mus musculus

  • Matched Description: responsible for approximately 90% of the kidney's reabsorption of glucose, and can be found in the S1 … kidney. There are some drugs that inhibit SGLT2 and are used to decrease blood sugar in patients with type 2 diabetes mellitus.
  • Matched Compounds: Aldosterone
  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3A … Neutral and basic amino acid transport protein rBAT
  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

  • Disease

    SMP0000086

    Pw000131 View Pathway
    Metabolite

    Ibuprofen Action Pathway

    Homo sapiens

  • Matched Description: Ibuprofen is a very common NSAID drug used to treat pain and inflammation. This includes headaches … , muscle pain and fever. It is sold under the brand name Advil or Motrin. Ibuprofen is typically … prostaglandin G/H synthase (COX). These enzymes are available as COX1 and COX2, and are encoded by … PTGS1 (COX1) and PTGS2 (COX2). Ibuprofen may also inhibit fatty acid amide hydrolase (FAAH), which
  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))
  • Matched Protein Synonyms: Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20
  • Matched Compound Synonyms: 20-oh-leukotriene b4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-ltb4 … 20-carboxy-leukotriene b4

  • Drug Action

    SMP0120866

    Pw122127 View Pathway
    Metabolite

    Blue Diaper Syndrome

    Rattus norvegicus

  • Matched Description: symptoms can include bacterial infections, damage to various parts of the eye, hypercalcemia, and impaired … hypercalcemia, and a tryptophan restricted diet to prevent all systems. If bacterial infections are common, antibiotics may be prescribed.
  • Matched Compounds: Aldosterone
  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT
  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

  • Disease

    SMP0120647

    Pw121903 View Pathway
    Metabolite

    Blue Diaper Syndrome

    Mus musculus

  • Matched Description: symptoms can include bacterial infections, damage to various parts of the eye, hypercalcemia, and impaired … hypercalcemia, and a tryptophan restricted diet to prevent all systems. If bacterial infections are common, antibiotics may be prescribed.
  • Matched Compounds: Aldosterone
  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3A … Neutral and basic amino acid transport protein rBAT
  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

  • Disease

    SMP0119376

    Pw120599 View Pathway
    Metabolite

    Kidney Function

    Bos taurus

  • Matched Description: angiotensin II and aldosterone, which increases sodium chloride reabsorption. This results in an … , nutrient reabsorption, and regulating electrolyte concentrations, acid-base balance, extracellular fluid … volume, and blood pressure. The early proximal tubule is where glucose, amino acids, sodium … , chlorine, phosphate, bicarbonate, and water are reabsorbed. Only water is reabsorbed in the thin descending … loop of Henle, while sodium, chlorine and potassium are reabsorbed in the thick ascending loop of
  • Matched Compounds: Aldosterone
  • Matched Proteins: Solute carrier family 3 (Activators of dibasic and neutral amino acid transport), member 2 … Solute carrier family 3 (Cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1
  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

  • Physiological

    SMP0120546

    Pw121802 View Pathway
    Metabolite

    Hartnup Disorder

    Mus musculus

  • Matched Description: -isoleucine, L-leucine, L-phenylalanine, L-serine, L-threonine, L-tryptophan, L-valine, and L-tyrosine in … urine. Symptoms include pellagra, psychosis, ataxia, and mental retardation. Treatment includes nicotinamide.
  • Matched Compounds: Aldosterone
  • Matched Proteins: Sodium- and chloride-dependent transporter XTRP3A … Neutral and basic amino acid transport protein rBAT
  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

  • Disease