SMP0071788
View Pathway
|
Phosphatidylethanolamine Biosynthesis PE(20:1(11Z)/20:1(11Z))
Arabidopsis thaliana
Matched Description: cell membranes, and contrary to phosphatidylcholine, it is concentrated with phosphatidylserine in … clarity. Instead, they are indicated with a dark green colour and appear to be free floating in the … dehydrogenase [NAD(+)] catalyzes the interconversion of glycerone phosphate (from glycolysis) and glycerol 3 … catalyzes the synthesis of phosphatidylserine from L-serine and a CDP-diacylglycerol. Last
Matched Compounds: DG(20:1(11Z)/20:1(11Z)/0:0) … PE(20:1(11Z)/20:1(11Z)) … PA(20:1(11Z)/20:1(11Z)) … LysoPA(20:1(11Z)/0:0) … CDP-DG(20:1(11Z)/20:1(11Z))
Matched Compound Synonyms: Dag(20:1/20:1) … Dag(20:1n9/20:1n9) … Dag(20:1w9/20:1w9) … Dg(20:1/20:1) … Dg(20:1n9/20:1n9)
|
SMP0124478
View Pathway
|
Ifosfamide Alkylating Agent Action Pathway
Homo sapiens
Matched Description: , acrolein is produced which is a potent lung irritant and causes hemorrhagic cystitis. Side effects of … ifosfamide is myelosuppression, immunosuppression and hemorrhagic cystitis (caused by acrolein).
Matched Protein Synonyms: Cytochrome P450 MP-20
Matched Compound Synonyms: Magnacide h and b
|
SMP0000369
View Pathway
|
Tyrosinemia Type 2 (or Richner-Hanhart Syndrome)
Homo sapiens
Matched Description: excess tyrosine to accumulate in the blood and urine, tyrosine crystals to form in the cornea, and … increased excretion in the urine of 4-hydroxyphenylpyruvic acid, hydroxyphenyllactic acid, and p … -hydroxyphenylacetic acid. Symptoms commonly appear in early childhood and include: mental retardation … , photophobia (increased sensitivity to light), excessive tearing, eye redness and pain and skin … lesions of the palms and soles. The patient is treated with restriction of dietary phenylalanine and
Matched Compound Synonyms: 2-oxo-3-phenylpropanoic acid (mixture oxo and keto) … Ammonia (conc 20% or greater) … [oh(oh)] … Ammonia (conc 20% or greater) … [oh(oh)]
|
SMP0120511
View Pathway
|
Tyrosinemia Type 3 (TYRO3)
Mus musculus
Matched Description: causes tyrosine and phenylalanine to accumulate in the blood resulting in increased excretion of … tyrosine in the urine. Tyrosinemia type 3 symptoms include: seizures, mental retardation and intermittent ataxia (occasional loss of balance and coordination).
Matched Compound Synonyms: 2-oxo-3-phenylpropanoic acid (mixture oxo and keto) … Ammonia (conc 20% or greater) … [oh(oh)] … Ammonia (conc 20% or greater) … [oh(oh)]
|
SMP0120540
View Pathway
|
Phenylketonuria
Mus musculus
Matched Description: Phenylketonuria, also called Folling disease, is a rare inborn error of metabolism (IEM) and … disorder is characterized by a large accumulation of phenylalanine in the blood and other tissues … . Symptoms of the disorder include behavioural problems, psychiatric disorders and seizures. Treatment
Matched Compound Synonyms: 2-oxo-3-phenylpropanoic acid (mixture oxo and keto) … Ammonia (conc 20% or greater) … [oh(oh)] … Ammonia (conc 20% or greater) … [oh(oh)]
|
SMP0125603
View Pathway
|
Tyrosinemia Type 2 (or Richner-Hanhart Syndrome)
Homo sapiens
Matched Description: excess tyrosine to accumulate in the blood and urine, tyrosine crystals to form in the cornea, and … increased excretion in the urine of 4-hydroxyphenylpyruvic acid, hydroxyphenyllactic acid, and p … -hydroxyphenylacetic acid. Symptoms commonly appear in early childhood and include: mental retardation … , photophobia (increased sensitivity to light), excessive tearing, eye redness and pain and skin … lesions of the palms and soles. The patient is treated with restriction of dietary phenylalanine and
Matched Compound Synonyms: 2-oxo-3-phenylpropanoic acid (mixture oxo and keto) … Ammonia (conc 20% or greater) … [oh(oh)] … Ammonia (conc 20% or greater) … [oh(oh)]
|
SMP0126539
View Pathway
|
Norelgestromin Action Pathway
Homo sapiens
Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD … 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD
Matched Compound Synonyms: 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one … 3b-hydroxypregn-5-en-20-one … 3beta-hydroxypregn-5-en-20-one
|
SMP0122609
View Pathway
|
Phenylalanine Metabolism
Drosophila melanogaster
Matched Description: or substrates that feed into catabolic processes like the citric acid cycle and glycolysis. L
Matched Compound Synonyms: 2-oxo-3-phenylpropanoic acid (mixture oxo and keto) … Ammonia (conc 20% or greater) … [oh(oh)]
|
SMP0063890
View Pathway
|
Phosphatidylcholine Biosynthesis PC(20:1(13Z)/20:1(13Z))
Arabidopsis thaliana
Matched Description: and has both structural and signalling roles. In eukaryotes, there exist two phosphatidylcholine … biosynthesis pathways: the Kennedy pathway and the methylation pathway. The Kennedy pathway begins … -choline and subsequently phosphatidylcholine. It is the major synthesis route in animals. The … . Instead, they are indicated with a dark green colour and appear to be free floating in the cytosol … ethanolamine by phospholipase D. The two methylated intermediates N-methylethanolamine phosphate and N
Matched Compounds: PS(20:1(13Z)/20:1(13Z)) … PE(20:1(13Z)/20:1(13Z)) … PE-NMe(20:1(13Z)/20:1(13Z)) … PE-NMe2(20:1(13Z)/20:1(13Z)) … PC(20:1(13Z)/20:1(13Z))
Matched Compound Synonyms: Ps(20:1n7/20:1n7) … Ps(20:1w7/20:1w7) … Pser(20:1(13z)/20:1(13z)) … Pser(20:1/20:1) … Pser(20:1n7/20:1n7)
|
SMP0071784
View Pathway
|
Phosphatidylethanolamine Biosynthesis PE(20:0/20:1(11Z))
Arabidopsis thaliana
Matched Description: cell membranes, and contrary to phosphatidylcholine, it is concentrated with phosphatidylserine in … clarity. Instead, they are indicated with a dark green colour and appear to be free floating in the … dehydrogenase [NAD(+)] catalyzes the interconversion of glycerone phosphate (from glycolysis) and glycerol 3 … catalyzes the synthesis of phosphatidylserine from L-serine and a CDP-diacylglycerol. Last
Matched Compounds: DG(20:0/20:1(11Z)/0:0) … PE(20:0/20:1(11Z)) … PA(20:0/20:1(11Z)) … LysoPA(20:0/0:0) … CDP-DG(20:0/20:1(11Z))
Matched Compound Synonyms: Dag(20:0/20:1) … Dag(20:0/20:1n9) … Dag(20:0/20:1w9) … Dg(20:0/20:1) … Dg(20:0/20:1n9)
|