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Matched Description: Buclizine is an antihistamine and antiemetic drug for the treatment of allergy symptoms and … prevention of nausea and vomiting. H1-antihistamines interfere with the agonist action of histamine at the … H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such … as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors … in T-cells to inhibit the immune response, in blood vessels to constrict dilated blood vessels, and

Matched Description: -like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3, and H4 … . Histamine receptor H1 belongs to the family of G-protein-coupled receptors (GPCRs), and it is … expressed in smooth muscles, on vascular endothelial cells, in the heart, and in the central nervous … system. It is linked to an intracellular G-protein (Gαq) that activates phospholipase C and the … release and expression of the NF-κB immune response transcription factor. H1-antihistamines inactivate

Matched Description: Mirabegron is a beta-3 adrenergic receptor agonist that is used to treat overactive bladder and … found under the brand name Myrbetriq and allows for the relaxation of detrusor smooth muscle of the … adenylyl cyclase. Once Mirabegron is administered and it binds to the beta-3 adrenergic receptor, the G … protein signalling cascade begins. The alpha and beta/gamma subunits of the G protein separate and … targets and inhibits MLCK through decreased calcium levels causing muscle relaxation. PKA can

Matched Description: -like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3, and H4 … . Histamine receptor H1 belongs to the family of G-protein-coupled receptors (GPCRs), and it is … expressed in smooth muscles, on vascular endothelial cells, in the heart, and in the central nervous … system. It is linked to an intracellular G-protein (Gαq) that activates phospholipase C and the … release and expression of the NF-κB immune response transcription factor. H1-antihistamines inactivate

Matched Description: -like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3, and H4 … . Histamine receptor H1 belongs to the family of G-protein-coupled receptors (GPCRs), and it is … expressed in smooth muscles, on vascular endothelial cells, in the heart, and in the central nervous … system. It is linked to an intracellular G-protein (Gαq) that activates phospholipase C and the … release and expression of the NF-κB immune response transcription factor. H1-antihistamines inactivate

Matched Description: Clenbuterol is a beta-2 adrenergic agonist used as a bronchodilator. This drug is taken orally and … is used for the treatment of asthma, bronchitis, and COPD. It exerts its effect through activation … signalling. Once clenbuterol is administered and it binds to the beta-2 adrenergic receptor, the G protein … signalling cascade begins. The alpha and beta/gamma subunits of the G protein separate and GDP is … and inhibits MLCK through decreased calcium levels causing muscle relaxation. PKA can phosphorylate

Matched Description: Dimenhydrinate is an H1-antihistamine and medication used to prevent and treat nausea, vomiting … , vertigo, and motion sickness.. H1-antihistamines interfere with the agonist action of histamine at the … H1 receptor and are administered to attenuate inflammatory process in order to treat conditions … such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 … , and in smooth muscles of lungs and intestines to relax those muscles. H1-antihistamines interfere

Matched Description: mechanism that regulates virulence and biofilm formation in response to bacterial population density. At … low population density, the fsr operon, which consists of the genes fsrA, fsrB, fsrC, and fsrD, is … expressed at basal levels, producing the FsrB, FsrC, and FsrD proteins. FsrD serves as the precursor … FsrD into mature GBAP, which is then cyclized into its active lactone form and exported to the … extracellular environment. As the bacterial population grows, the concentration of GBAP accumulates, and

Matched Description: and chronic bronchitis. It accomplishes this by upon inhalation of the drug by relaxing smooth … muscles in the airways to improve breathing. It can be found under the brand name Brovana, and it has a … 2 fold greater potency than racemic formoterol. Once arformoterol is administered and it binds to … the beta-2 adrenergic receptor, the G protein signalling cascade begins. The alpha and beta/gamma … subunits of the G protein separate and GDP is replaced with GTP on the alpha subunit. This alpha subunit

Matched Description: is used as a bronchodilator for the treatment of asthma and relief from bronchospasm. The result of … taking this drug is relaxation of the bronchial smooth muscles causing bronchodilaton and increased … airflow. Once pirbuterol is administered and it binds to the beta-2 adrenergic receptor, the G … protein signalling cascade begins. The alpha and beta/gamma subunits of the G protein separate and GDP … and inhibits MLCK through decreased calcium levels causing muscle relaxation. PKA can phosphorylate