SMP0501492
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Thiosulfate Disproportionation III
Escherichia coli APEC O1
Matched Description: atom from sulfur donors to nucleophilic sulfur acceptors, and it has been found in many major phyla … (prokaryotic and eukaryotic). The role of thiosulfate sulfurtransferase might be the detoxification of … cyanide in both bacteria and mammals, or it might also involve in formation of prosthetic groups in … iron-sulfur proteins. In this pathway, thiosulfate and hydrogen cyanide have been catalyzed by … thiosulfate sulfurtransferase to form thiocyanate and sulfite. Sulfite is used in later sulfur metabolism.
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SMP0478035
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Thiosulfate Disproportionation III
Prevotella bivia DSM 20514
Matched Description: atom from sulfur donors to nucleophilic sulfur acceptors, and it has been found in many major phyla … (prokaryotic and eukaryotic). The role of thiosulfate sulfurtransferase might be the detoxification of … cyanide in both bacteria and mammals, or it might also involve in formation of prosthetic groups in … iron-sulfur proteins. In this pathway, thiosulfate and hydrogen cyanide have been catalyzed by … thiosulfate sulfurtransferase to form thiocyanate and sulfite. Sulfite is used in later sulfur metabolism.
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SMP0499808
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Thiosulfate Disproportionation III
Bacteroides coprocola
Matched Description: atom from sulfur donors to nucleophilic sulfur acceptors, and it has been found in many major phyla … (prokaryotic and eukaryotic). The role of thiosulfate sulfurtransferase might be the detoxification of … cyanide in both bacteria and mammals, or it might also involve in formation of prosthetic groups in … iron-sulfur proteins. In this pathway, thiosulfate and hydrogen cyanide have been catalyzed by … thiosulfate sulfurtransferase to form thiocyanate and sulfite. Sulfite is used in later sulfur metabolism.
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SMP0000606
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Tamoxifen Metabolism Pathway
Homo sapiens
Matched Description: breast cancer. Tamoxifen itself only has weak anti-estrogen effects and must be converted into more … active metabolites to have therapeutic activity. Metabolism takes place in the liver and is carried out … primarily by cytochrome P450 enzymes. Tamoxifen is hydroxylated by CYP2D6 and demethylated by CYP3A4 … and CYP3A5, producing the active metabolites 4-hydroxytamoxifen and endoxifen. These metabolites
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SMP0120956
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Classical Complement Pathway
Rattus norvegicus
Matched Description: system within the immune system. This pathway begins with the activation of antibodies IgM and IgG … . Protein C3 is created, and after a series of reactions, cleaves the C5 protein. This brings phagocytes … to the infected area and sets the stage for the coming together of the membrane attack complex (MAC … ). This complex targets the cell and creates an opening in the membrane, which leads to cell lysis and death.
Immunological
Cellular Response
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SMP0126173
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Sulodexide Action Pathway
Homo sapiens
Matched Description: Sulodexide mixture of glycosaminoglycans (GAGs), dermatan sulfate (DS) and fast-moving heparin. Its … conversion of prothrombin and thrombin. Doing that also inhibits the conversion of fibrinogen to fibrin … mainly metabolized by the liver. It is eliminated through renal, fecal and bile routes, and sometimes … and dizziness. Some allergic reactions can cause skin rash but these occurrences are rare.
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SMP0126752
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Neomycin Action Pathway
Homo sapiens
Matched Description: tablet and as a topical ointment to treat bacterial infections. Neomycin is derived from Streptomyces … fradiae by-products. There are three components A, B, and C, component B is the most active. This … aminoglycoside is effective against gram-positive and gram-negative bacteria. It acts by binding to the … 30S ribosomal subunit disrupting protein synthesis and inhibiting further translation. Specifically … occur, although a prolonged administration can cause the risk of neurotoxicity, ototoxicity, and nephrotoxicity in humans.
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SMP0478411
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Thiosulfate Disproportionation III
Alistipes indistinctus YIT 12060
Matched Description: atom from sulfur donors to nucleophilic sulfur acceptors, and it has been found in many major phyla … (prokaryotic and eukaryotic). The role of thiosulfate sulfurtransferase might be the detoxification of … cyanide in both bacteria and mammals, or it might also involve in formation of prosthetic groups in … iron-sulfur proteins. In this pathway, thiosulfate and hydrogen cyanide have been catalyzed by … thiosulfate sulfurtransferase to form thiocyanate and sulfite. Sulfite is used in later sulfur metabolism.
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SMP0475380
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Thiosulfate Disproportionation III
Methylococcus capsulatus
Matched Description: atom from sulfur donors to nucleophilic sulfur acceptors, and it has been found in many major phyla … (prokaryotic and eukaryotic). The role of thiosulfate sulfurtransferase might be the detoxification of … cyanide in both bacteria and mammals, or it might also involve in formation of prosthetic groups in … iron-sulfur proteins. In this pathway, thiosulfate and hydrogen cyanide have been catalyzed by … thiosulfate sulfurtransferase to form thiocyanate and sulfite. Sulfite is used in later sulfur metabolism.
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SMP0666866
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Thiosulfate Disproportionation III
Pseudomonas aeruginosa
Matched Description: atom from sulfur donors to nucleophilic sulfur acceptors, and it has been found in many major phyla … (prokaryotic and eukaryotic). The role of thiosulfate sulfurtransferase might be the detoxification of … cyanide in both bacteria and mammals, or it might also involve in formation of prosthetic groups in … iron-sulfur proteins. In this pathway, thiosulfate and hydrogen cyanide have been catalyzed by … thiosulfate sulfurtransferase to form thiocyanate and sulfite. Sulfite is used in later sulfur metabolism.
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