SMP0063814
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Complement Pathway
Homo sapiens
Matched Description: a protease that can work at the same time, and it cleaves complement factor B into factors Ba and Bb … . the C3(H2O) complex can bind to factor Bb, which is a C3 convertase, and works to cleave factor C3 … into C3a and C3b more quickly. The C3(H2O)Bb complex also binds factor B, leading to easier … cleavage into Ba and Bb by factor D. Following this, complement factor C3b can bind to the surface of cells … , and on host cells, proteins on the cell membrane can bind to C3b, preventing it from forming
Immunological
Kinase Signaling
Pathogen-Activated Signaling
Cellular Response
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SMP0120903
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Complement Pathway
Mus musculus
Matched Description: a protease that can work at the same time, and it cleaves complement factor B into factors Ba and Bb … . the C3(H2O) complex can bind to factor Bb, which is a C3 convertase, and works to cleave factor C3 … into C3a and C3b more quickly. The C3(H2O)Bb complex also binds factor B, leading to easier … cleavage into Ba and Bb by factor D. Following this, complement factor C3b can bind to the surface of cells … , and on host cells, proteins on the cell membrane can bind to C3b, preventing it from forming
Immunological
Kinase Signaling
Pathogen-Activated Signaling
Cellular Response
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SMP0120927
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Complement Pathway
Bos taurus
Matched Description: a protease that can work at the same time, and it cleaves complement factor B into factors Ba and Bb … . the C3(H2O) complex can bind to factor Bb, which is a C3 convertase, and works to cleave factor C3 … into C3a and C3b more quickly. The C3(H2O)Bb complex also binds factor B, leading to easier … cleavage into Ba and Bb by factor D. Following this, complement factor C3b can bind to the surface of cells … , and on host cells, proteins on the cell membrane can bind to C3b, preventing it from forming
Immunological
Kinase Signaling
Pathogen-Activated Signaling
Cellular Response
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SMP0120905
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Ubiquitin–Proteasome Pathway
Mus musculus
Matched Description: effects in many other pathways and processes. This pathway uses 2 distinct steps. The first step is that … . This pathway is important for DNA repair, regulating the amount of proteins, and the creation of antigen-peptide.
Matched Proteins: STIP1 homology and U box-containing protein 1
Transport/Degradation
Cellular Response
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SMP0407945
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Lipopolysaccharide Biosynthesis
Halococcus morrhuae DSM 1307
Matched Description: either the fructose 6-phosphate produced by glycolysis and pyruvate dehydrogenase or obtained from the … and a glucosamine 6-phosphate. The latter compound is isomerized through a phosphoglucosamine mutase … through a bifunctional protein glmU resulting in a Coenzyme A, hydrogen ion and N-acetyl-glucosamine 1 … -phosphate. The latter interacts with UTP and hydrogen ion through the bifunctional protein glmU … resulting in a pyrophosphate and a UDP-N-acetylglucosamine. UDP-N-acetylglucosamine iinteracts with (3R)-3
Matched Proteins: Xanthine and Co dehydrogenase maturation factor
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SMP0644882
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Oxidative Phosphorylation
Odoribacter laneus YIT 12061
Matched Description: acid, resulting in a fumaric acid and ubiquinol.
Ubiquinone interacts with succinic acid through a … cofactors, ferroheme b, 2FE-2S, FAD, and 3Fe-4S iron-sulfur cluster.
Then 2 ubiquinol interact with … oxygen and 4 hydrogen ion through a cytochrome bd-I terminal oxidase resulting in a 4 hydrogen ion … transferred into the periplasmic space, 2 water returned into the cytoplasm and 2 ubiquinone, which … and 4 hydrogen ion through a cytochrome bd-II terminal oxidase resulting in a 4 hydrogen ion
Matched Proteins: Succinate dehydrogenase and fumarate reductase iron-sulfur protein
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SMP0063651
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Phosphatidylinositol Phosphate Metabolism
Mus musculus
Matched Description: different phosphoinositides have been identified in mammals, each distinguished by the number and/or … cell, such as actin cytoskeletal reorganization, membrane transport, and cell proliferation. They … may also affect protein localization, aggregation, and activity by acting as secondary messengers. The … signals means that their synthesis and metabolism must be tightly regulated. Synthesis begins with the … a number of specific phosphoinositide kinases and phosphatases, which add (kinase) and remove
Matched Proteins: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
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SMP0120929
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Ubiquitin–Proteasome Pathway
Bos taurus
Matched Description: effects in many other pathways and processes. This pathway uses 2 distinct steps. The first step is that … . This pathway is important for DNA repair, regulating the amount of proteins, and the creation of antigen-peptide.
Matched Proteins: STIP1 homology and U-box containing protein 1
Transport/Degradation
Cellular Response
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SMP0120937
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Toll-Like Receptor Pathway 2
Bos taurus
Matched Description: and recognizes conserved microbial molecules. TLRs get their name from the toll gene in Drosophila … , double stranded RNA, flagellin and others. Recognition of pathogen molecules allows the immune system … bacteria. It associates with two other proteins, monocyte differentiation antigen CD14, and lymphocyte … signalling to the toll/interleukin-1 receptor domain-containing adaptor protein (TIRAP) and Toll … -interacting protein (TOLLIP), which then recruit MyD99 and IRAK1 to the TLR on the cell surface.
Other
Matched Proteins: TGF-beta activated kinase 1 and MAP3K7 binding protein 3
Immunological
Pathogen-Activated Signaling
Gene Regulatory
Cellular Response
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SMP0120961
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Toll-Like Receptor Pathway 2
Rattus norvegicus
Matched Description: and recognizes conserved microbial molecules. TLRs get their name from the toll gene in Drosophila … , double stranded RNA, flagellin and others. Recognition of pathogen molecules allows the immune system … bacteria. It associates with two other proteins, monocyte differentiation antigen CD14, and lymphocyte … signalling to the toll/interleukin-1 receptor domain-containing adaptor protein (TIRAP) and Toll … -interacting protein (TOLLIP), which then recruit MyD99 and IRAK1 to the TLR on the cell surface.
Other
Matched Proteins: TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
Immunological
Pathogen-Activated Signaling
Gene Regulatory
Cellular Response
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