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Matched Description: ABC transporter without phosphorylation. Allose-6-phosphate isomerase and allulose-6-phosphate 3 … -epimerase catalyze the remaining reactions resulting in D-allulose 6 phosphate and Beta-D-fructofuranose … 6-phosphate respectively. Once Beta D fructofuranose 6-phosphate is synthesized, it can be used in the glycolysis and pyruvatedehydrogenase pathway.

Matched Description: ABC transporter without phosphorylation. Allose-6-phosphate isomerase and allulose-6-phosphate 3 … -epimerase catalyze the remaining reactions resulting in D-allulose 6 phosphate and Beta-D-fructofuranose … 6-phosphate respectively. Once Beta D fructofuranose 6-phosphate is synthesized, it can be used in the glycolysis and pyruvatedehydrogenase pathway.

Matched Description: ABC transporter without phosphorylation. Allose-6-phosphate isomerase and allulose-6-phosphate 3 … -epimerase catalyze the remaining reactions resulting in D-allulose 6 phosphate and Beta-D-fructofuranose … 6-phosphate respectively. Once Beta D fructofuranose 6-phosphate is synthesized, it can be used in the glycolysis and pyruvatedehydrogenase pathway.

Matched Description: Atactica Polyneurtiformis; Hereditary Motor and Sensory Neuropathy IV; HSMN4; Adult Refsum Disease I … chromosome 10 (adult Refsum disease I), and by mutation of the PEX7 gene. A defect in phytanoyl-CoA … due to the inability for phytanic acid to undergo alpha and beta oxidation. Symptoms include anosmia … , ataxia, nystagmus, neurological deterioration and peripheral neuropathy. Adult Refsum disease is … distinctly different from Infantile Refsum disease both genetically and phenotypically. Infantile

Matched Description: growth and cytoskeletal reorganization. Rac1 activity is regulated by guanine nucleotide exchange factors … (GEFs). GEFs cause the release of GDP, allowing GDP to bind and Rac1 to become activated. GTPase … effectors to cytoskeleton reorganization. PAK1 phosphorylates and activates LIM kinase. LIM kinase then … phosphorylates cofilin, inactivating it leading to reduced actin filament severing and depolymerization … , therby increasing polymerized actin. Rac1 stimulates lamellipodia and filopodia formation which are

Matched Description: binding sites, and as it is cardioselective, it binds primarily to those in the heart. Esmolol is … injected intravenously, and when it enters the heart, it binds to the beta-1 adrenergic receptor … , preventing signalling. Normally, epinephrine and norepinephrine bind to the beta-1 adrenergic receptor … with equal affinity and trigger a G-protein signalling cascade that result in the heart muscle … contracting. When esmolol binds, it causes the rate and force of these heart contractions to be decreased

Matched Description: Ketone bodies are consisted of acetone, beta-hydroxybutyrate and acetoacetate. In liver cells … ' mitochondria, acetyl-CoA can synthesize acetoacetate and beta-hydroxybutyrate; and spontaneous … irreversibly by 3-oxoacid CoA-transferase 1 that also coupled with interconversion of succinyl-CoA and … dehydrogenase to form (R)-3-Hydroxybutyric acid with NADH. Ketogenesis occurs mostly during fasting and … starvation. Stored fatty acids will be broken down and mobilized to produce large amount of acetyl

Matched Description: Sphingolipids have important structural and functional roles. They can be associated with membrane … cholesterol and assist in forming specialized membrane domains. Sphingolipids, similar to … their sphingosine core, a long-chain amino alcohol. sphingomyelins and glycosphingolipids are … palmitoyl-CoA and serine producing 3-keto-dihydrosphingosine by serine palmitoyltransferase. 3-Keto … dihydroceramide. Dihydroceramide is then dehyrogenated to ceramide. Ceramides are a sphingosine and fatty acid

Matched Description: maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter … phase, and thus, the action potential duration to be prolonged. The excitability of the cell is … reduced and this leads to a slowing of the heart rate. The QRS duration is increased and the QT interval … is also prolonged. These effects on the action potentials and the heart rate, therefore, mean that

Matched Description: , coughing up blood, bruising and difficulty breathing and or swallowing. Desirudin binds to the active … formation of a blood clot. This is usually administered subcutaneously, it is then metabolized and … eliminated via the kidney. Due to the anticoagulant properties herbs and supplements with anticoagulant and … antiplatelet activity should be avoided, this includes ginger, garlic, bilberry, danshen, piracetam and ginkgo biloba.