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Matched Description: mellitus (NIDDM)). It is structurally similar to acetohexamide, chlorpropamide, and tolazamide … membrane and potassium efflux. This binding results in the depolarization of the cell. In consequence, it

Matched Description: H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are … , allergic conjunctivitis, and urticaria. Wakefulness is regulated by histamine in the tuberomammillary

Matched Description: -positive and gram-negative infections. Clavulanic acid, when administered with amoxicillin, can cause … some mild gastrointestinal adverse effects. These include vomiting, nausea, loose stools, and

Matched Description: open, calcium ions enter the cell, and the influx of intracellular calcium concentration stimulates … the secretion of insulin. Glimepiride bypasses this process by DIRECTLY forcing SUR1 closed and stimulating increased insulin secretion.

Matched Description: and many gram-negative organisms. It acts by inhibiting the dihydropteroate synthase, an important … effects of this treatment include itching, burning, redness, and swelling. Long-term use of this drug may result in cancer of the thyroid gland.

Matched Description: a longer duration and may require less frequent dosing. This can result in a more sustained effect … respiratory smooth muscle cells, vascular endothelial cells, the gastrointestinal tract, and immune cells

Matched Description: can enter the systemic cirulation, and most of GLP-1 are degraded by dipeptidyl peptidase-4

Matched Description: Apomorphine is a non-ergoline dopamine agonist with high binding affinity to dopamine D2, D3, and

Matched Description: interferes with the initiation of protein synthesis and with proper protein elongation. This eventually leads to bacterial cell death.

Matched Description: that degrades fibrin clots. In addition to its binding and activation on fibrin clots, PLG also … present in humans - type I plasminogen contains two glycosylation moieties (N-linked to N289 and O … , including tissue plasminogen activator (tPA), urokinase plasminogen activator (uPA), kallikrein, and … urokinase plasminogen activator. The conversion of plasminogen to plasmin involves the cleavage of the peptide bond between Arg-561 and Val-562.