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Matched Description: hydrog ions and 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one or 2,5-Diamino-6 … -hydroxy-4-(5-phosphoribosylamino)pyrimidine. Either of these compounds interacts with a water molecule and … -phosphoribosylamino)uracil reductase resulting in an ammonium and 5-amino-6-(5-phospho-D … resulting in the release of a NADP and a 5-amino-6-(5-phospho-D-ribitylamino)uracil. This compound … resulting in a release of a phosphate, and a 5-amino-6-(D-ribitylamino)uracil. D-ribulose 5

Matched Description: and oxidative stress. This pathway is one of the hydrogen sulfide biosynthesis pathways (totally … two). L-Cysteine is transported by L-cysteine ABC transporter and convert to 3-mercaptopyruvic acid by … pyruvic acid and hydrogen sulfide by 3-mercaptopyruvate sulfurtransferase.

Matched Description: , water and a 2-aminoprop-2-enoate. This compound in turn reacts spontaneously to produces 2 … -iminipropanoate. This compound in turn reacts with water and hydrogen ion spontaneously resulting in the release of ammonium and apyruvate.

Matched Description: and management of Brucellosis, mycoplasma infection, acne vulgaris, chlamydial infection; chronic … subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is … reversible in nature. Clomocycline is lipophilic and can easily pass through the cell membrane or

Matched Description: and for organophosphate anticholinesterase/pesticides poisoning. Atropine is an alkaloid … originating from the plant Atropa Betalldonna and can be found in some other plants. Naturally it is a racemic … mixture of equal parts d-hyoscyamine and l-hyoscyamine. Althought is is classified as a muscarinic … bradycardia and asystole produced by choline esters, anticholinesterase agents, parasympathomimetic … ) factor. In clinical dose administrations it counteracts the peripheral dilation and low blood

Matched Description: is administered orally and is metabolized by carboylesterase1 into its active metabolite (ACT-333679 … ). The metabolite has a high selectivity for prostacyclin receptor that activates it and subsequent … G coupled protein, Gs, that increases cAMP levels. Increased cAMP levels leads to inhibited platelet aggregation and activation.

Matched Description: , allowing more solute and water reabsorption. Diphenoxylate binds to opioid receptors, mainly the mu … are coupled to Gi and Go proteins. The Gi cascade results in an inhibition of adenylate cyclase … , which reduces cytosolic cAMP. Protein kinase A is activated by cAMP to open Ca2+ channels and allow Ca2 … + influx into the cytosol. A reduction in cAMP reduces the activity of protein kinase A and thus … reduces the cytosolic Ca2+. The Go signaling cascade results in activation of K+ channels and inhibition

Matched Description: and salt retention associated with congestive heart failure. In the distal convoluted tubule (DCT … ), the regulation of ions such as sodium, potassium, calcium, chloride, and magnesium occurs. In … the interstitium-blood area and K+ into the epithelial cell; the Na+/Ca2+ exchanger, which pumps Na … + into the cell and Ca2+ into the interstitium-blood; and the chloride transporter which transports … epithelial cell, and a Na+/Cl- cotransporter which transports Na+ and Cl- into the epithelial cell

Matched Description: Fosamprenavir is an antiretroviral agent and prodrug of amprenavir used for the treatment and … protease. The HIV virus binds and penetrates host cell. Viral RNA is transcribed into viral DNA via … reverse transcriptase. Viral DNA enters the host nucleus and is integrated into the host DNA via … capsid and matrix protein to form the outer protein shell, and Pol encodes for the reverse … transcriptase and integrase protein to synthesize and incorporate its genome into host cells. HIV-1 protease

Matched Description: receptor-mediated endocytosis. The lipoviroparticles attach to LDL-R and SR-B1, and then the virus … binds to CD81 and subsequently claudin-1 and occludin, which mediate the late steps of viral entry. The … virion and translated at the rough endoplasmic reticulum into a single Genome polyprotein. The … genome polyprotein is cleaved by host and viral proteases into 10 viral proteins. The nucleocapsid … protein core and the two envelope proteins E1 and E2 form the N terminus of the polyprotein and are the