Browsing Search Results

Matched Description: incorporation into DNA and RNA as well as by inhibiting thymidylate synthase. Since thymidine

Matched Description: of itraconazole is only 55% and is best when taken with food. Itraconazole is transported from the … cassette sub-family C member 3. Once there, it travels to the liver and is transported in via P … Lanosterol 14-alpha demethylase, the first step in steroid biosynthesis and a very similar enzyme to what it … 3A7, Cytochrome P450 3A4, Cytochrome P450 2B6, and Cytochrome P450 2E1, which are similar to

Matched Description: consists of six iodine atoms and achieves water solubility by ionization; thus, it is a 3.0 ratio

Matched Description: protein. The inhibition of matrix protein 2 prevents the virus from replicating and further infecting cells.

Matched Description: that degrades fibrin clots. In addition to its binding and activation on fibrin clots, PLG also … present in humans - type I plasminogen contains two glycosylation moieties (N-linked to N289 and O … , including tissue plasminogen activator (tPA), urokinase plasminogen activator (uPA), kallikrein, and … urokinase plasminogen activator. The conversion of plasminogen to plasmin involves the cleavage of the peptide bond between Arg-561 and Val-562.

Matched Description: of glycogen (a stored form of glucose), fats, and many amino acids. At beginning, acetyl-CoA first … called alpha-ketoglutarate) and then a second carboxyl group (leading to the 4-carbon compound called … succinate). Succinate molecule is further oxidized to fumarate, then malate and finally

Matched Description: of glycogen (a stored form of glucose), fats, and many amino acids. At beginning, acetyl-CoA first … called alpha-ketoglutarate) and then a second carboxyl group (leading to the 4-carbon compound called … succinate). Succinate molecule is further oxidized to fumarate, then malate and finally

Matched Description: Sesquiterpenoids have 15 carbons and three isoprene units. They are derived from farnesyl … squalene synthase 1. Then, the same enzyme removes the pyrophosphate group and replaces it with a … (+)-alpha-barbatene, if it interacts wtih beta-chamigrene synthase it forms (+)-beta-chamigrene, and

Matched Description: Propofol is injected intravenously where 95-99% of the drug is bound to serum albumin and … hemoglobin. 1-5% of it goes to the brain and skeletal muscles to preform its mechanism of action. The rest … possibility that 4-Hydroxypropofol does not metabolize into further metabolites and remains as is

Matched Description: United States for obesity treatment. Mazindol stimulates the nervous system and suppresses the appetite … through the reuptake of norepinephrine and dopamine, which prolongs their duration in the synapse so … released into the synapse when the neuron is stimulated and fires. Mazindol binds to the sodium-dependent