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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 528574 results

SMP0126770

Pw128374 View Pathway
Metabolite

Omadacycline Action Pathway

Homo sapiens

  • Matched Description: pneumonia. It acts by binding to the 30S ribosomal subunit blocking protein synthesis and disrupting … bacterial function leading to cell death. Omadacycline should be taken on an empty stomach and … multivalent ions and antacids should be avoided whilst taking omadacycline.

  • Drug Action

    SMP0126839

    Pw128444 View Pathway
    Metabolite

    Coagulation Factor VII Human Action Pathway

    Homo sapiens

  • Matched Description: Coagulation factor VII human is a coagulation factor also known as Balfaxar, Beriplex, Kcentra and … Octaplex to treat hemophilia and Glanzmann's thrombasthenia. It is administered intravenously it … subsequently activate coagulation factor X and IX leading to blood clotting formation. It is broken down via catabolism in the body.

  • Drug Action

    SMP0120836

    Pw122097 View Pathway
    Metabolite

    Glycogenosis, Type III. Cori Disease, Debrancher Glycogenosis

    Rattus norvegicus

  • Matched Description: of GSD-III is higher in North African Jews (1 in 5 400), Faroese (1 in 3 100) and the Inuit … is structurally abnormal and impairs the function of certain organs and tissues, especially the … liver and muscles. GSD III typically presents during infancy with hypoglycemia and failure to thrive … . Clinical examination usually reveals hepatomegaly. Muscular disease, including hypotonia and … cardiomyopathy, usually occurs later in life. GSD III is divided into the types IIIa, IIIb, IIIc, and IIId

  • Disease

    SMP0120955

    Pw122218 View Pathway
    Protein

    Toll-Like Receptor Pathway 1

    Rattus norvegicus

  • Matched Description: lipoproteins, peptidoglycans, lipotechoic acids, and mannan. TLR3 recognizes viral double-stranded … RNA, small interfering RNAsa, and self-RNAs. TLR4 recognizes lipopolysaccharides. TLR7 recognizes … single-stranded RNA. TLR9 recognizes bacterial and viral DNA with unmethylated CpG-DNA motifs. TLRs … are synthesized in the endoplasmic reticulum, moved to the Golgi, and then recruited to the cell … . MYD88 is recruited by all TLRs. Adaptor TIRAP recruits MYD88 to cell surface TLRs, including TLR2 and
  • Matched Proteins: TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

  • Immunological
    Pathogen-Activated Signaling
    Gene Regulatory
    Cellular Response

    SMP0120617

    Pw121873 View Pathway
    Metabolite

    Glycogenosis, Type III. Cori Disease, Debrancher Glycogenosis

    Mus musculus

  • Matched Description: of GSD-III is higher in North African Jews (1 in 5 400), Faroese (1 in 3 100) and the Inuit … is structurally abnormal and impairs the function of certain organs and tissues, especially the … liver and muscles. GSD III typically presents during infancy with hypoglycemia and failure to thrive … . Clinical examination usually reveals hepatomegaly. Muscular disease, including hypotonia and … cardiomyopathy, usually occurs later in life. GSD III is divided into the types IIIa, IIIb, IIIc, and IIId

  • Disease

    SMP0125939

    Pw127511 View Pathway
    Metabolite

    Lopinavir Action Pathway

    Homo sapiens

  • Matched Description: human immunodeficiency virus (HIV) infection. Lopinavir is marketed and administered exclusively in … bioavailability and extensive biotransformation. The HIV virus binds and penetrates the host cell. Viral RNA … is transcribed into viral DNA via reverse transcriptase. Viral DNA enters the host nucleus and is … polyprotein, where Gag encodes for the capsid and matrix protein to form the outer protein shell, and … Pol encodes for the reverse transcriptase and integrase protein to synthesize and incorporate its

  • Drug Action

    SMP0126496

    Pw128095 View Pathway
    Metabolite

    Racepinephrine A1-Adrenergic Vasoconstriction Action Pathway

    Homo sapiens

  • Matched Description: Asthmanefrin and is orally inhaled to act on both alpha and beta adrenergic receptors. This drug has a … rapid onset and short duration and acts as a smooth muscle relaxant and constrictor in different … to relax the smooth muscle of the lungs, and it is also an alpha-1 adrenergic receptor agonist which … the hydrostatic pressure and consequently bronchial mucosal edema. Racepinephrine is a racemic … mixture consisting of d-Epinephrine and l-Epinephrine enantiomers. Epinephrine is a non-selective α- and β

  • Drug Action

    SMP0126576

    Pw128177 View Pathway
    Metabolite

    Acepromazine Dopamine Antagonist Action Pathway

    Homo sapiens

  • Matched Description: Acepromazine is a phenothiazine tranquilizer that blocks dopamine receptors in the CNS and … in animals as a sedative and antiemetic. Its principal value is in quietening and calming anxious … dopaminergic-receptors (subtypes D1, D2, D3 and D4 - different antipsychotic properties on … productive and unproductive symptoms), on serotonergic-receptors (5-HT1 and 5-HT2, with anxiolytic … , antidepressive and antiaggressive properties as well as an attenuation of extrapyramidal side-effects, but

  • Drug Action

    SMP0125759

    Pw127326 View Pathway
    Metabolite

    Glycogenosis, Type III. Cori Disease, Debrancher Glycogenosis

    Homo sapiens

  • Matched Description: of GSD-III is higher in North African Jews (1 in 5 400), Faroese (1 in 3 100) and the Inuit … is structurally abnormal and impairs the function of certain organs and tissues, especially the … liver and muscles. GSD III typically presents during infancy with hypoglycemia and failure to thrive … . Clinical examination usually reveals hepatomegaly. Muscular disease, including hypotonia and … cardiomyopathy, usually occurs later in life. GSD III is divided into the types IIIa, IIIb, IIIc, and IIId

  • Disease

    SMP0002122

    Pw002110 View Pathway
    Metabolite

    L-Cysteine Degradation

    Escherichia coli

  • Matched Description: in the release of a hydrogen sulfide, a hydrogen ion and a a 2-aminoprop-2-enoate. The latter … spontaneously with water and a hydrogen ion resulting in the release of ammonium and pyruvate.

  • Metabolic